Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics

YH Choi, HK Han - Journal of pharmaceutical investigation, 2018 - Springer
Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …

Nanotechnology: a promising approach for delivery of neuroprotective drugs

S Naqvi, A Panghal, SJS Flora - Frontiers in Neuroscience, 2020 - frontiersin.org
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues

K Madaan, S Kumar, N Poonia, V Lather… - Journal of Pharmacy …, 2014 - journals.lww.com
Dendrimers are the emerging polymeric architectures that are known for their defined
structures, versatility in drug delivery and high functionality whose properties resemble with …

PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery

D Luong, P Kesharwani, R Deshmukh, MCIM Amin… - Acta biomaterialia, 2016 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are well-defined, highly branched,
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …

Recent advances in targeted drug delivery strategy for enhancing oncotherapy

J Li, Q Wang, G Xia, N Adilijiang, Y Li, Z Hou, Z Fan… - Pharmaceutics, 2023 - mdpi.com
Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately
deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile …

Nanodrugs: pharmacokinetics and safety

S Onoue, S Yamada, HK Chan - International journal of …, 2014 - Taylor & Francis
To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …

Current trends of targeted therapy for oral squamous cell carcinoma

H Li, Y Zhang, M Xu, D Yang - Journal of cancer research and clinical …, 2022 - Springer
Oral squamous cell carcinoma (OSCC) is a malignant disease in the world which has a
profound effect on human health and life quality. According to tumor stage and pathological …

Dendrimers in combination with natural products and analogues as anti-cancer agents

S Mignani, J Rodrigues, H Tomas… - Chemical Society …, 2018 - pubs.rsc.org
For the first time, an overview of dendrimers in combination with natural products and
analogues as anti-cancer agents is presented. This reflects the development of drug delivery …

Injectable in situ forming thermo-responsive graphene based hydrogels for cancer chemo-photothermal therapy and NIR light-enhanced antibacterial applications

R Lima-Sousa, D de Melo-Diogo, CG Alves… - Materials Science and …, 2020 - Elsevier
Functionalized graphene oxide (GO) and reduced GO (rGO) based nanomaterials hold a
great potential for cancer photothermal therapy. However, their systemic administration has …