GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

C Castiello, P Junghanns, A Mergel, C Jacob… - Green …, 2023 - pubs.rsc.org
Green chemistry has become a hot topic and the focus of not only many companies but also
researchers. Green chemistry strives to identify alternative and environmentally friendly …

Application of Life Cycle Assessment in the Pharmaceutical Industry: A Critical Review

Z Chen, JZ Lian, H Zhu, J Zhang, Y Zhang… - Journal of Cleaner …, 2024 - Elsevier
The pharmaceutical industry presents unique challenges and opportunities for mitigating
global environmental impacts. This paper reviewed studies utilizing Life Cycle Assessment …

Operationally simple, scalable synthesis of aryloxy propanolamines using glycerol as a green promoting media: Practical eco-friendly access to propranolol and …

M Saquib, MF Khan, J Singh, B Khan, P Kumar… - Sustainable Chemistry …, 2022 - Elsevier
Herein, the development of an efficient and practical, glycerol promoted, green and
sustainable synthesis of diversified aryloxy propanolamines, including propranolol and …

Synthetic and Chromatographic Challenges and Strategies for Multigram Manufacture of KRASG12C Inhibitors

G Nikitidis, ACC Carlsson, S Karlsson… - … Process Research & …, 2021 - ACS Publications
In one of our drug development projects, we identified potent KRASG12C inhibitors for
treatment of cancer. For our early preclinical studies, we needed a strategy to enable supply …

Case study on environmental safety and sustainability of pharmaceutical production based on life cycle assessment of enrofloxacin

W Kong, B Lv, S Yang, H Shen, G Jing… - Journal of Environmental …, 2021 - Elsevier
Pharmaceutical industry plays an important role in protecting human health and promoting
economic development, but it also responsible for serious environmental issues. Thus, to …

Entomopathogenic fungi in crops protection with an emphasis on bioactive metabolites and biological activities

M Shahbaz, K Palaniveloo, YS Tan… - World Journal of …, 2024 - Springer
Plant pathogens with their abundance are harmful and cause huge damage to different
agricultural crops and economy of a country as well as lead towards the shortage of food for …

Recent Advances in Green Chemistry Approaches for Pharmaceutical Synthesis

S Ahmad, R Jaiswal, R Yadav, S Verma - Sustainable Chemistry One World, 2024 - Elsevier
Green chemistry has revolutionized pharmaceutical synthesis by promoting sustainability
and reducing environmental impact. This review aims to present the recent advancements in …

New Trends in Sample Preparation for Pharmaceutical and Biological Analysis by Chromatographic Methods

M Contin, C Dobrecky, S Flor… - Recent Advances in …, 2022 - books.google.com
Sample preparation is the rate-limiting step in the success of an analytical methodology. It is
needed not only to clean–up and concentrate the sample but to avoid the matrix effect and to …

Isotopic (D/H) management of chemical and biological processes properties: applications in pharmaceutical engineering

IV Kazimova, EV Uspenskaya… - E3S Web of …, 2023 - e3s-conferences.org
The strategy of sustainable industrial development in accordance with “green chemistry”
stimulates researchers to search for a “lever” that could provide control over the direction …

Biomarkers for Cancer Immunotherapy

H Ahsan, SU Islam, MB Ahmed, YS Lee… - Cancer Biomarkers in …, 2022 - Springer
Management of advanced-stage cancers of various types has revolutionized with the
introduction of immune checkpoint inhibitors (ICIs) in 2010. However, achievement of …