Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Gallium-68 (68Ga) is a positron-emitting isotope used for clinical PET imaging of peptide
receptor expression. 68Ga radiopharmaceuticals used in molecular PET imaging consist of …

The clinical impact and accessibility of 68Ga tracers for the prostate-specific membrane
antigen (PSMA) and other targets would be greatly enhanced by the availability of a simple …

The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Extensive angiogenesis is a characteristic feature in the synovial tissue of rheumatoid
arthritis (RA) from a very early stage of the disease onward and constitutes a crucial event …

Molecular radiopharmaceuticals based on bioconjugates of chelators with peptides and
proteins have had significant clinical impact in the diagnosis and treatment of several types …

The ability to append targeting biomolecules to chelators that efficiently coordinate to the
diagnostic imaging radionuclide, 99mTc, and the therapeutic radionuclide, 188Re, can …

Radionuclide imaging is now the premier imaging method in clinical practice for its high
sensitivity and tomographic capability. Current clinically available radio imaging methods …

This work reports the synthesis of three multimeric RGD peptidomimetic‐paclitaxel
conjugates featuring a number of αVβ3 integrin ligands ranging from 2 to 4. These …