Poly (N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications

K Nagase, M Yamato, H Kanazawa, T Okano - Biomaterials, 2018 - Elsevier
Thermoresponsive surfaces, prepared by grafting of poly (N-isopropylacrylamide)(PIPAAm)
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …

Cell sheet tissue engineering: cell sheet preparation, harvesting/manipulation, and transplantation

J Kobayashi, A Kikuchi, T Aoyagi… - Journal of biomedical …, 2019 - Wiley Online Library
Cell sheet tissue engineering is a concept for creating transplantable two‐dimensional (2D)
and three‐dimensional (3D) tissues and organs. This review describes three elements of …

Brushing up functional materials

S Ma, X Zhang, B Yu, F Zhou - NPG Asia Materials, 2019 - nature.com
Surface-grafting polymer brushes (SPB), which are used in a versatile technique to easily
realize surface modifications, can be commonly used to change the inherent surface …

Thermoresponsive interfaces obtained using poly (N-isopropylacrylamide)-based copolymer for bioseparation and tissue engineering applications

K Nagase - Advances in Colloid and Interface Science, 2021 - Elsevier
Abstract Poly (N-isopropylacrylamide)(PNIPAAm) is the most well-known and widely used
stimuli-responsive polymer in the biomedical field owing to its ability to undergo temperature …

Dynamically tunable cell culture platforms for tissue engineering and mechanobiology

K Uto, JH Tsui, CA DeForest, DH Kim - Progress in polymer science, 2017 - Elsevier
Human tissues are sophisticated ensembles of many distinct cell types embedded in the
complex, but well-defined, structures of the extracellular matrix (ECM). Dynamic …

Advances in cell culture: anchorage dependence

OW Merten - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
Anchorage-dependent cells are of great interest for various biotechnological applications.(i)
They represent a formidable production means of viruses for vaccination purposes at very …

[HTML][HTML] Cell sheet technology as an engineering-based approach to bone regeneration

Q You, M Lu, Z Li, Y Zhou, C Tu - International Journal of …, 2022 - ncbi.nlm.nih.gov
Bone defects that are congenital or the result of infection, malignancy, or trauma represent a
challenge to the global healthcare system. To address this issue, multiple research groups …

Design of temperature-responsive polymer-grafted surfaces for cell sheet preparation and manipulation

J Kobayashi, T Okano - Bulletin of the Chemical Society of …, 2019 - academic.oup.com
This review focuses on the design of poly (N-isopropylacrylamide)(PIPAAm)-grafted
surfaces for cell sheet preparation and manipulation, which are revolutionary tools for the …

Enhanced pulsatile drug release from injectable magnetic hydrogels with embedded thermosensitive microgels

S Campbell, D Maitland, T Hoare - ACS Macro Letters, 2015 - ACS Publications
Nanocomposite in situ-gelling hydrogels containing both superparamagnetic iron oxide
nanoparticles (SPIONs) and thermoresponsive microgels are demonstrated to facilitate …

Carrier-free functionalized multidrug nanorods for synergistic cancer therapy

M Zhou, X Zhang, Y Yang, Z Liu, B Tian, J Jie, X Zhang - Biomaterials, 2013 - Elsevier
We developed carrier-free multidrug nanocrystals (MDNCs) for the combination
chemotherapy with synergistic effect, improved tolerance and imaging capability for cancer …