Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

INTRODUCTION Although the cerebellum has long been considered to be a purely motor
structure, recent studies have revealed that it also has critical nonmotor functions. Cerebellar …

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a
worldwide prevalence of about 1%, characterized by impairments in social interaction …

The mechanistic target of rapamycin (mTOR) signaling pathway is a crucial cellular
signaling hub that, like the nervous system itself, integrates internal and external cues to …

Cerebellar abnormalities, particularly in Right Crus I (RCrusI), are consistently reported in
autism spectrum disorders (ASD). Although RCrusI is functionally connected with ASD …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic …

BACKGROUND Neurodevelopmental disorders are caused by abnormalities in the
developing brain. Such abnormalities can occur as a result of germline or somatic mutations …

Abstract PI3K-AKT/mTOR signaling pathway represents an essential signaling mechanism
for mammalian enzyme-related receptors in transducing signals or biological processes …

Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single …