Prevalence of familial hypercholesterolemia among the general population and patients with atherosclerotic cardiovascular disease: a systematic review and meta …

P Hu, KI Dharmayat, CAT Stevens, MTA Sharabiani… - Circulation, 2020 - Am Heart Assoc
Background: Contemporary studies suggest that familial hypercholesterolemia (FH) is more
frequent than previously reported and increasingly recognized as affecting individuals of all …

The genetics and screening of familial hypercholesterolaemia

R Henderson, M O'Kane, V McGilligan… - Journal of biomedical …, 2016 - Springer
Familial Hypercholesterolaemia is an autosomal, dominant genetic disorder that leads to
elevated blood cholesterol and a dramatically increased risk of atherosclerosis. It is …

[HTML][HTML] Dyslipidemia management for primary prevention of cardiovascular events: Best in-clinic practices

N Thongtang, R Sukmawan, EJB Llanes… - Preventive Medicine …, 2022 - Elsevier
Dyslipidemia is a fundamental risk factor for cardiovascular diseases (CVDs) and can
worsen the prognosis, if unaddressed. Lipid guidelines are still evolving as dyslipidemia is …

Alirocumab in pediatric patients with heterozygous familial hypercholesterolemia: a randomized clinical trial

RD Santos, A Wiegman, S Caprio, B Cariou… - JAMA …, 2024 - jamanetwork.com
Importance Many pediatric patients with heterozygous familial hypercholesterolemia (HeFH)
cannot reach recommended low-density lipoprotein cholesterol (LDL-C) concentrations on …

Epidemiology of familial hypercholesterolaemia: community and clinical

AJ Vallejo-Vaz, KK Ray - Atherosclerosis, 2018 - Elsevier
Familial hypercholesterolaemia (FH) is a genetic disorder affecting the metabolism of low-
density lipoprotein (LDL) particles, leading to high LDL-cholesterol levels maintained over …

Familial hypercholesterolemia: a systematic review of guidelines on genetic testing and patient management

G Migliara, V Baccolini, A Rosso, E D'Andrea… - Frontiers in Public …, 2017 - frontiersin.org
Background Familial hypercholesterolemia (FH) is an autosomal-dominant hereditary
disorder of lipid metabolism that causes lifelong exposure to increased LDL levels resulting …

Consensus clinical recommendations for the management of plasma lipid disorders in the Middle East: 2021 update

N Alsayed, W Almahmeed, F Alnouri, K Al-Waili… - Atherosclerosis, 2022 - Elsevier
Background and aims Disorders of plasma lipids remain key risk factors for the development
of atherosclerotic cardiovascular disease (ASCVD) in the Middle East and are estimated to …

Cardiovascular risk profile and lipid management in the population-based cohort study LATINO: 20 years of real-world data

C Gavina, DS Carvalho, M Pardal… - Journal of Clinical …, 2022 - mdpi.com
The rising prevalence of cardiovascular (CV) risk factors in Portugal has translated into more
than 35,000 annual deaths due to CV diseases. We performed a multicenter observational …

Familial hypercholesterolemia (FH) registry worldwide: A systematic review

A Amerizadeh, SH Javanmard, N Sarrafzadegan… - Current Problems in …, 2022 - Elsevier
Familial hypercholesterolemia (FH) is the most common genetic disease which accelerates
the development of premature coronary artery disease (CAD) in young adults if remains …

[HTML][HTML] Serum lipid profile and clinical characteristics of patients with xanthelasma palpebrarum

H Kavoussi, A Ebrahimi, M Rezaei… - Anais Brasileiros de …, 2016 - SciELO Brasil
Background: Although many factors are involved in the etiology of xanthelasma palpebrum,
lipid disorder is strongly associated with its induction. Xanthelasma palpebrum, the most …