[HTML][HTML] Mesenchymal stem cells current clinical applications: a systematic review

DE Rodríguez-Fuentes, LE Fernández-Garza… - Archives of medical …, 2021 - Elsevier
Introduction Human Mesenchymal Stem Cells (hMSCs) are multipotent stem cells capable of
renewing themselves and differentiation in vitro into different kinds of tissues. In vivo hMSCs …

[HTML][HTML] Immunomodulatory properties of mesenchymal stromal cells: an update

L Müller, A Tunger, M Wobus, M von Bonin… - Frontiers in cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to
modulate the phenotype and functional properties of various immune cells that play an …

[HTML][HTML] Mesenchymal stem cell-based therapy for rheumatoid arthritis

M Sarsenova, A Issabekova, S Abisheva… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of
cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to …

[HTML][HTML] Mesenchymal stromal cell secretome for the treatment of immune-mediated inflammatory diseases: latest trends in isolation, content optimization and delivery …

E Munoz-Perez, A Gonzalez-Pujana, M Igartua… - Pharmaceutics, 2021 - mdpi.com
Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

[HTML][HTML] IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b

R Yang, H Huang, S Cui, Y Zhou, T Zhang… - Cell Death & …, 2020 - nature.com
Bone marrow mesenchymal stem cells (MSCs) have demonstrated therapeutic effects for
colitis through immunomodulation and anti-inflammation. However, whether MSC-derived …

Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition

J Galipeau, M Krampera, K Leblanc, JA Nolta… - Cytotherapy, 2021 - Elsevier
Abstract The International Society for Cell & Gene Therapy mesenchymal stromal cell (MSC)
committee has been an interested observer of community interests in all matters related to …

Strategies to address mesenchymal stem/stromal cell heterogeneity in immunomodulatory profiles to improve cell-based therapies

CM Dunn, S Kameishi, DW Grainger, T Okano - Acta Biomaterialia, 2021 - Elsevier
Mesenchymal stromal cells (MSCs) have gained immense attention over the past two
decades due to their multipotent differentiation potential and pro-regenerative and …

WJMSC‐derived small extracellular vesicle enhance T cell suppression through PD‐L1

M Li, R Soder, S Abhyankar… - Journal of …, 2021 - Wiley Online Library
Both mesenchymal stem cells (MSCs) and their corresponding small extracellular vesicles
(sEVs, commonly referred to as exosomes) share similar immunomodulatory properties that …

[HTML][HTML] Human induced pluripotent stem cell-derived mesenchymal stem cells acquire rejuvenation and reduced heterogeneity

W Wruck, N Graffmann, LS Spitzhorn… - Frontiers in Cell and …, 2021 - frontiersin.org
Despite the uniform selection criteria for the isolation of human mesenchymal stem cells
(MSCs), considerable heterogeneity exists which reflects the distinct tissue origins and …

Dissecting the relationship between antimicrobial peptides and mesenchymal stem cells

AÉ Silva-Carvalho, MH Cardoso, T Alencar-Silva… - Pharmacology & …, 2022 - Elsevier
Among the various biological properties presented by Mesenchymal Stem Cells (MSCs),
their ability to control the immune response and fight pathogen infection through the …