Antioxidant intake and antitumor therapy: toward nutritional recommendations for optimal results
N Mut-Salud, PJ Álvarez, JM Garrido… - Oxidative Medicine …, 2016 - Wiley Online Library
The role of the induction of oxidative stress as the mechanism of action of many antitumor
drugs is acquiring an increasing interest. In such cases, the antitumor therapy success may …
drugs is acquiring an increasing interest. In such cases, the antitumor therapy success may …
Updates on oxaliplatin-induced peripheral neurotoxicity (OXAIPN)
AA Argyriou - Toxics, 2015 - mdpi.com
Oxaliplatin-induced peripheral neuropathy (OXAIPN) is of great clinical interest as it ranks
among the most common dose limiting toxicities of oxaliplatin (OXA) administration with an …
among the most common dose limiting toxicities of oxaliplatin (OXA) administration with an …
Curcumin alleviates oxaliplatin-induced peripheral neuropathic pain through inhibiting oxidative stress-mediated activation of NF-κB and mitigating inflammation
X Zhang, Z Guan, X Wang, D Sun, D Wang… - Biological and …, 2020 - jstage.jst.go.jp
Oxaliplatin is a first-line clinical drug in cancer treatment and its side effects of peripheral
neuropathic pain have also attracted much attention. Neuroinflammation induced by …
neuropathic pain have also attracted much attention. Neuroinflammation induced by …
NET-triggered NLRP3 activation and IL18 release drive oxaliplatin-induced peripheral neuropathy
T Lin, L Hu, F Hu, K Li, CY Wang, LJ Zong… - Cancer immunology …, 2022 - AACR
Oxaliplatin is an antineoplastic agent frequently used in the treatment of gastrointestinal
tumors. However, it causes dose-limiting sensorimotor neuropathy, referred to as oxaliplatin …
tumors. However, it causes dose-limiting sensorimotor neuropathy, referred to as oxaliplatin …
Blocking PAR2 attenuates oxaliplatin-induced neuropathic pain via TRPV1 and releases of substance P and CGRP in superficial dorsal horn of spinal cord
K Chen, ZF Zhang, MF Liao, WL Yao, J Wang… - Journal of the …, 2015 - Elsevier
Oxaliplatin (OXL) is a third-generation chemotherapeutic agent commonly used to treat
metastatic digestive tumors; however, neuropathic pain is one of the main limiting …
metastatic digestive tumors; however, neuropathic pain is one of the main limiting …
Participation of pro-inflammatory cytokines in neuropathic pain evoked by chemotherapeutic oxaliplatin via central GABAergic pathway
D Xu, H Zhao, H Gao, H Zhao, D Liu, J Li - Molecular pain, 2018 - journals.sagepub.com
Background Neuropathic pain is observed in patients as chemotherapeutic oxaliplatin is
used to treat metastatic digestive tumors; however, the mechanisms responsible for …
used to treat metastatic digestive tumors; however, the mechanisms responsible for …
Molecular testing to deliver personalized chemotherapy recommendations: risking over and undertreatment
Background In the adjuvant setting of cancer treatment, de-escalation strategies have the
goal of omitting or minimizing treatment in patients, without compromising outcomes …
goal of omitting or minimizing treatment in patients, without compromising outcomes …
Engagement of microRNA-155 in exaggerated oxidative stress signal and TRPA1 in the dorsal horn of the spinal cord and neuropathic pain during chemotherapeutic …
F Miao, R Wang, G Cui, X Li, T Wang, X Li - Neurotoxicity research, 2019 - Springer
Oxaliplatin (OXL) is a third-generation chemotherapeutic agent commonly used to treat
metastatic digestive tumors, but one of the main limiting complications of OXL is painful …
metastatic digestive tumors, but one of the main limiting complications of OXL is painful …
Oxaliplatin added to fluoropyrimidine for adjuvant treatment of colorectal cancer is associated with long-term impairment of peripheral nerve sensory function and …
M Stefansson, P Nygren - Acta Oncologica, 2016 - Taylor & Francis
Background: Oxaliplatin-induced peripheral neuropathy (OIPN) of acute and chronic type is
well known, but long-term chronic type OIPN and its impact on quality of life (QoL) has not …
well known, but long-term chronic type OIPN and its impact on quality of life (QoL) has not …
Acupuncture May Help to Prevent Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Sham-Controlled, Single-Blind Study
Objective This study investigated the efficacy of acupuncture in preventing chemotherapy-
induced peripheral neuropathy (CIPN) in patients with colorectal cancer (CRC). Methods …
induced peripheral neuropathy (CIPN) in patients with colorectal cancer (CRC). Methods …