Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …

Parkinson's disease (PD) is the second most common neurodegenerative disorder and the
fastest growing neurologic disease in the world, yet no disease-modifying therapy is …

α-Synuclein is a protein with a molecular weight of 14.5 kDa and consists of 140 amino
acids encoded by the SNCA gene. Missense mutations and gene duplications in the SNCA …

A plethora of studies indicate that iron metabolism is dysregulated in Parkinson's disease
(PD). The literature reveals well-documented alterations consistent with established dogma …

Parkinson disease (PD) is the second-most common neurodegenerative disease. The
characteristic pathology of progressive dopaminergic neuronal loss in people with PD is …

The complexity of Alzheimer's disease (AD) complicates the search for effective treatments.
While the key roles of pathologically modified proteins has occupied a central role in …

Oxidative disruption of dopaminergic neurons is regarded as a crucial pathogenesis in
Parkinson's disease (PD), eventually causing neurodegenerative progression.(-) …

Focal iron accumulation associated with brain iron dyshomeostasis is a pathological
hallmark of various neurodegenerative diseases (NDD). The application of iron-sensitive …

Abstract Parkinson's disease (PD), the second most common neurodegenerative movement
disorder, is characterized by progressive motor and non-motor symptoms [1]. Despite …

There is an emerging link between the accumulation of iron in the brain and abnormal tau
pathology in a number of neurodegenerative disorders, such as Alzheimer's disease (AD) …