Sleep-wake disorders are highly prevalent disorders, which can lead to negative effects on
cognitive, emotional and interpersonal functioning, and can cause maladaptive metabolic …

Under normal circadian function, metabolic control is temporally coordinated across tissues
and behaviors with a 24-h period. However, circadian disruption results in negative …

Evening-oriented sleep timing preferences have been associated with risk of diabetes,
cardiovascular diseases, obesity, psychiatric disorders, and increased mortality. This …

Dietary prebiotics produce favorable changes in the commensal gut microbiome and reduce
host vulnerability to stress-induced disruptions in complex behaviors such as sleep. The …

Studies have confirmed that insomnia is related to gut microbiota. Previous research
suggests that immunity and metabolism are also associated with insomnia. However, to our …

Sleep has evolved as a universal core function to allow for restorative biological processes.
Detailed knowledge of metabolic changes necessary for the sleep state in the brain is …

The seed of Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex HF Chou (ZSS) is often used as
a traditional Chinese medicine for insomnia due to its sedative and hypnotic effects, but the …

Context People characterized as late chronotype have elevated type 2 diabetes and
cardiovascular disease risk compared to early chronotype. It is unclear how chronotype is …

Abstract Study Objectives Individuals with evening chronotype have a higher risk of
cardiovascular and metabolic disorders, although the underlying mechanisms are not well …

Short and long sleep duration are associated with adverse metabolic outcomes, such as
obesity and diabetes. We evaluated cross-sectional differences in metabolite levels between …