Background Autism spectrum disorders (ASD) are characterised by abnormalities in social
interaction and communication skills, as well as stereotypic behaviours and restricted …

Depression is among the most disabling and costly illnesses in the world. Despite good
short-term efficacy outcomes in the treatment of depression, long-term outcomes remain …

Objectives: There is growing recognition that a comprehensive economic assessment of a
new health‐care intervention at the time of launch requires both a cost‐effectiveness …

BackgroundConcern is widespread about potential sponsorship influence on research,
especially in pharmacoeconomic studies. Quantitative analysis of possible bias in such …

Background: When guidelines for health economic evaluations prescribe that a societal
perspective should be adopted, productivity costs should be included. However, previous …

BACKGROUND: High levels of public spending, rising costs of treatments and scarcity of
mental health resources have intensified the need for information on the cost-effectiveness …

The criteria used to assess whether a problem is of public health importance (and therefore
should be a priority for health services) include the prevalence of the problem, the severity of …

Many patients with epilepsy suffer from persistent seizures despite maximal antiepileptic
drug (AED) therapy. Chronic, intermittent vagus nerve stimulation (VNS) has proven to be a …

Stresses for the psychologist called on for expert testimony stem from (1) the general nature
of court procedure and (2) the" special stresses which inhere in the present position of …

Objectives: It has long been suggested that, whereas the results of clinical studies of
pharmaceuticals are generalizable from one jurisdiction to another, the results of economic …