Neutrophils in cancer carcinogenesis and metastasis

S Xiong, L Dong, L Cheng - Journal of hematology & oncology, 2021 - Springer
In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Soluble urokinase plasminogen activator receptor (suPAR) as a biomarker of systemic chronic inflammation

LJH Rasmussen, JEV Petersen… - Frontiers in …, 2021 - frontiersin.org
Systemic chronic inflammation (SCI) is persistent, health-damaging, low-grade inflammation
that plays a major role in immunosenescence and in development and progression of many …

Obesity and cancer: existing and new hypotheses for a causal connection

TW Stone, M McPherson, LG Darlington - EBioMedicine, 2018 - thelancet.com
Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of
dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly …

Modulation of cellular function by the urokinase receptor signalling: A mechanistic view

D Alfano, P Franco, MP Stoppelli - Frontiers in Cell and …, 2022 - frontiersin.org
Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-
inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease …

The systemic-level repercussions of cancer-associated inflammation mediators produced in the tumor microenvironment

D Aguilar-Cazares, R Chavez-Dominguez… - Frontiers in …, 2022 - frontiersin.org
The tumor microenvironment is a dynamic, complex, and redundant network of interactions
between tumor, immune, and stromal cells. In this intricate environment, cells communicate …

Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records

J Watson, C Salisbury, J Banks, P Whiting… - British journal of …, 2019 - nature.com
Background Early identification of cancer in primary care is important and challenging. This
study examined the diagnostic utility of inflammatory markers (C-reactive protein, erythrocyte …

Association between elevated suPAR, a new biomarker of inflammation, and accelerated aging

LJH Rasmussen, A Caspi, A Ambler… - The Journals of …, 2021 - academic.oup.com
Background To understand and measure the association between chronic inflammation,
aging, and age-related diseases, broadly applicable standard biomarkers of systemic …

The urokinase receptor: a multifunctional receptor in cancer cell biology. therapeutic implications

A Li Santi, F Napolitano, N Montuori… - International journal of …, 2021 - mdpi.com
Proteolysis is a key event in several biological processes; proteolysis must be tightly
controlled because its improper activation leads to dramatic consequences. Deregulation of …

Electrochemical detection of c-reactive protein based on anthraquinone-labeled antibody using a screen-printed graphene electrode

S Jampasa, W Siangproh, R Laocharoensuk… - Talanta, 2018 - Elsevier
In this present work, a novel electrochemical immunosensor employing a screen-printed
graphene electrode (SPGE) for a simple and highly sensitive determination of C-reactive …

Electrochemiluminescence aptasensor with dual signal amplification by silica nanochannel-based confinement effect on nanocatalyst and efficient emitter enrichment …

N Ma, S Xu, W Wu, J Liu - Molecules, 2023 - mdpi.com
The rapid and sensitive detection of the important biomarker C-reactive protein (CRP) is of
great significance for monitoring inflammation and tissue damage. In this work, an …