Stimuli-responsive polymeric micelles for the delivery of paclitaxel

H Yang, AR Khan, M Liu, M Fu, J Ji, L Chi… - Journal of Drug Delivery …, 2020 - Elsevier
Paclitaxel is an anti-tumor drug that is effective in the treatment of various tumors, but its
applications are limited due to its poor water solubility, short biological half-life and severe …

Gold nanoparticle-based drug nanocarriers as a targeted drug delivery system platform for cancer therapeutics: a systematic review

A Rosyidah, S Kerdtoob, WI Yudhistyra, AW Munfadlila - Gold Bulletin, 2023 - Springer
Cancer was the world's second major cause of death. Several treatments were available,
including chemotherapy, radiotherapy, immunotherapy, and surgery. However, they are …

Oxidative stress response's kinetics after 60 minutes at different (30% or 100%) normobaric hyperoxia exposures

C Leveque, S Mrakic-Sposta, P Lafère… - International journal of …, 2022 - mdpi.com
Oxygen is a powerful trigger for cellular reactions and is used in many pathologies, including
oxidative stress. However, the effects of oxygen over time and at different partial pressures …

Antigen targeting and anti-tumor activity of a novel anti-CD146 212Pb internalizing alpha-radioimmunoconjugate against malignant peritoneal mesothelioma

K Lindland, MM Malenge, RG Li, R Wouters… - Scientific Reports, 2024 - nature.com
Malignant mesothelioma, a highly aggressive cancer that primarily affects the serosal
membranes, has limited therapeutic options, particularly for cavitary tumors, such as …

Current advances in nanoformulations of therapeutic agents targeting tumor microenvironment to overcome drug resistance

S Fakhri, SZ Moradi, F Faraji, T Farhadi… - Cancer and Metastasis …, 2023 - Springer
The tumor microenvironment (TME) plays a pivotal role in cancer development and
progression. In this line, revealing the precise mechanisms of the TME and associated …

Malignant pleural mesothelioma: Genetic and microenviromental heterogeneity as an unexpected reading frame and therapeutic challenge

DM Abbott, C Bortolotto, S Benvenuti, A Lancia… - Cancers, 2020 - mdpi.com
Mesothelioma is a malignancy of serosal membranes including the peritoneum, pleura,
pericardium and the tunica vaginalis of the testes. Malignant mesothelioma (MM) is a rare …

Pleural mesothelioma: a snapshot of emerging drug targets and opportunities for non-surgical therapeutic advancement

JB Assié, D Jean - Expert Opinion on Therapeutic Targets, 2023 - Taylor & Francis
Introduction Pleural mesothelioma is a rare and aggressive cancer originating in the pleura,
with a devastating prognosis and limited treatment options. There have been significant …

Novel insights into mesothelioma therapy: emerging avenues and future prospects

L Kuryk, G Rodella, M Staniszewska, KW Pancer… - Frontiers in …, 2022 - frontiersin.org
Malignant mesothelioma is a rare and aggressive cancer that develops in the thin layer
surrounding the mesothelium and is mainly caused by asbestos exposure. Despite …

Feasibility and safety of extended pleurectomy/decortication for malignant pleural mesothelioma. A single group experience

F Falanga, P Rinaldi, C Primiceri, C Bortolotto… - Thoracic …, 2022 - Wiley Online Library
Surgery is part of a multimodal therapeutic approach to malignant pleural mesothelioma
(MPM) although its real beneficial effect is still controversial. The optimal precise sequence …

Sequential delivery of novel triple drug combination via crosslinked alginate/lactoferrin nanohybrids for enhanced breast cancer treatment

M Salah, MA Sallam, MA Abdelmoneem, M Teleb… - Pharmaceutics, 2022 - mdpi.com
While breast cancer remains a global health concern, the elaboration of rationally designed
drug combinations coupled with advanced biocompatible delivery systems offers new …