Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men. Adenocarcinoma accounts for 90% of CRC cases. There has been …

Ovarian cancer (OC) remains a fatal malignancy because most patients experience
recurrent disease, which is resistant to chemotherapy. The outcomes for patients with …

Cancer cell–derived extracellular vesicles (EVs) have unique protein profiles, making them
promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is …

Designed ankyrin repeat proteins (DARPins) can recognize targets with specificities and
affinities that equal or surpass those of antibodies, but because of their robustness and …

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein primarily
known to mediate homotypic cell contacts in epithelia tissues. Because EpCAM expression …

Injection of tumor cells in mice more than 30years ago resulted in the discovery of an
epithelial antigen, later defined as a cell adhesion molecule (EpCAM). Although EpCAM has …

A significant proportion of extracellular nucleic acids in plasma circulate highly protected in
tumor‐specific exosomes, but it is unclear how the release of exosomes is modulated in …

Carcinoma cells found in the blood of cancer patients are predictors of metastatic
progression and may guide treatment decisions. Most of the current strategies for detecting …

The ever-growing perception of cancer stem cells (CSCs) as a plastic state rather than a
hardwired defined entity has evolved our understanding of the functional and biological …

Prostate cancer (CaP) is the second leading malignancy in men. The role of epithelial cell
adhesion molecule (EpCAM), also known as CD326, in CaP progression and therapeutic …