[HTML][HTML] Obesity: a chronic low-grade inflammation and its markers

D Khanna, S Khanna, P Khanna, P Kahar, BM Patel - Cureus, 2022 - ncbi.nlm.nih.gov
As the prevalence of obesity continues to rise, the world is facing a major public health
concern. Obesity is a complex disease associated with an increase in several inflammatory …

The physiological functions of human peroxisomes

RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …

Structural and functional roles of ether lipids

JM Dean, IJ Lodhi - Protein & cell, 2018 - academic.oup.com
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which
the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether …

Lipidomics for studying metabolism

X Han - Nature Reviews Endocrinology, 2016 - nature.com
Many thousands of lipid species exist and their metabolism is interwoven via numerous
pathways and networks. These networks can also change in response to cellular …

Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance

G Enkavi, M Javanainen, W Kulig, T Róg… - Chemical …, 2019 - ACS Publications
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Plasmalogens and chronic inflammatory diseases

JC Bozelli Jr, S Azher, RM Epand - Frontiers in physiology, 2021 - frontiersin.org
It is becoming widely acknowledged that lipids play key roles in cellular function, regulating
a variety of biological processes. Lately, a subclass of glycerophospholipids, namely …

Obesity, inflammation and the immune system

FP De Heredia, S Gómez-Martínez… - Proceedings of the …, 2012 - cambridge.org
Obesity shares with most chronic diseases the presence of an inflammatory component,
which accounts for the development of metabolic disease and other associated health …

Novel biomarkers for pre‐diabetes identified by metabolomics

R Wang‐Sattler, Z Yu, C Herder… - Molecular systems …, 2012 - embopress.org
Type 2 diabetes (T2D) can be prevented in pre‐diabetic individuals with impaired glucose
tolerance (IGT). Here, we have used a metabolomics approach to identify candidate …

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction

H Khodabandehloo, S Gorgani-Firuzjaee… - Translational …, 2016 - Elsevier
Obesity is a major public health problem worldwide, and it is associated with an increased
risk of developing type 2 diabetes. It is now commonly accepted that chronic inflammation …

Lipidomic analysis of adipose-derived extracellular vesicles reveals specific EV lipid sorting informative of the obesity metabolic state

A Blandin, I Dugail, G Hilairet, M Ponnaiah… - Cell reports, 2023 - cell.com
Adipose extracellular vesicles (AdEVs) transport lipids that could participate in the
development of obesity-related metabolic dysfunctions. This study aims to define mouse …