Actin is a versatile and ubiquitous cytoskeletal protein that plays a major role in both the
establishment and the maintenance of neuronal polarity. For a long time, the most prominent …

Specialized adult somatic cells, such as cardiomyocytes (CMs), are highly differentiated with
poor renewal capacity, an integral reason underlying organ failure in disease and aging …

Highlights•Dendritic spines depend on the actin cytoskeleton and its remodeling for their
structure and plasticity.•Actin nucleation factors enable the formation and growth of distinct F …

Actin has well established functions in cellular morphogenesis. However, it is not well
understood how the various actin assemblies in a cell are kept in a dynamic equilibrium, in …

Liquid-liquid phase separation (LLPS) is involved in various dynamic biological
phenomena. In epithelial cells, dynamic regulation of junctional actin filaments tethered to …

The formation of axon collateral branches from the pre-existing shafts of axons is an
important aspect of neurodevelopment and the response of the nervous system to injury …

The egg-laying rate is an important indicator of egg production of laying ducks. Egg
production directly impacts the economic benefits of the duck industry. In order to obtain …

The actin cytoskeleton provides structural stability and adaptability to the cell. Neuronal
dendrites frequently undergo morphological changes by emanating, elongating, and …

Cells of multicellular organisms need to adopt specific morphologies. However, the
molecular mechanisms bringing about membrane topology changes are far from understood …

How signaling units spontaneously arise from a noisy cellular background is not well
understood. Here, we show that stochastic membrane deformations can nucleate …