Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …

Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

Background and Aims Dietary fat intake is associated with increased risk of colorectal
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …

Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal
muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic …

Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …

Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …

Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …

Highlights•Obesity is associated with chronic inflammation and chronic diseases.•Obesity is
associated with increased risk and progression of several cancers.•The mechanism by …

In inflammatory bowel disease (IBD), intestinal mucosa cell and intestinal epithelial cell are
severely damaged, and then their susceptibility to bacteria increases, so many commensal …

Objective: To determine the association of sarcopenia with postoperative morbidity and
mortality after colorectal surgery. Background: Functional compromise in elderly colorectal …