3D tumor models in urology

J Neuhaus, A Rabien, A Reinhold, L Koehler… - International Journal of …, 2023 - mdpi.com
Three-dimensional tumor models have become established in both basic and clinical
research. As multicellular systems consisting of tumor and tumor-associated cells, they can …

Genotypic Analysis of COL4A1 Gene in Diabetic Nephropathy and Type 2 Diabetes Mellitus Patients: A Comparative Genetic Study

N Shukla, S Kumari, P Verma, AS Kushwah… - DNA and Cell …, 2023 - liebertpub.com
Diabetic nephropathy (DN) is specified by microalbuminuria, glomerular lesions, and renal
fibrosis leading to end-stage renal disease. The pathophysiology of DN is multifactorial as a …

[HTML][HTML] Transglutaminase-mediated stiffening of the glomerular basement membrane mitigates pressure-induced reductions in molecular sieving coefficient by …

D Wang, N Ferrell - Matrix Biology, 2024 - Elsevier
Proteinuria, the presence of high molecular weight proteins in the urine, is a primary
indicator of chronic kidney disease. Proteinuria results from increased molecular …

Development of an in vitro 3D model of the proximal tubule interstitial interface as a high throughput renal fibrosis assay platform

E Tasinato - 2024 - theses.ncl.ac.uk
Chronic kidney disease (CKD) is a progressive, irreversible disease with a worldwide
prevalence of 10-13%. Hypertension and diabetes are the main causes of CKD, and they …