N Ye, JL Neumeyer, RJ Baldessarini, X Zhen, A Zhang - Chem. Rev, 2013 - academia.edu
Dopamine (DA) is a critical neurotransmitter in the mammalian central nervous system (CNS). The cerebral dopaminergic system is implicated in the pathophysiology of several …
An operationally simple and user-friendly new protocol for the synthesis of 3, 5-disubstituted/ annulated isothiazoles is devised utilizing β-ketodithioesters/β-ketothioamides and NH4OAc …
S Berenyi, C Csutoras, A Sipos - Current medicinal chemistry, 2009 - ingentaconnect.com
The most practical synthetic routes to the preparation of as important pharmaceuticals as oxycodone, naloxone, naltrexone, nalbuphine and buprenorphine have utilized the alkaloid …
S J. Finnema, B Bang-Andersen… - Current topics in …, 2010 - benthamdirect.com
Dopamine (DA) is known to play an important role in numerous brain functions and has been suggested to be involved in several neuropsychiatric and neurological disorders. From …
J Li, J Li, X Ji, Q Liu, L Chen… - Advanced Synthesis & …, 2021 - Wiley Online Library
A protocol was described to access diverse isothiazoles with functionalization potential via transition metal‐free three‐component annulation of alkynones, potassium ethylxanthate …
G Huang, J Li, X Ji, L Chen, Q Liu, X Chen… - Chemical …, 2020 - pubs.rsc.org
The use of potassium ethyl xanthate (EtOCS2k) as a sulfur atom donor enabled the transition-metal-free [3+ 1+ 1] cascade annulation of isopropene derivatives with NH4I in …
ST Kim, EJ Doukmak, RG Flax, DJ Gray… - ACS Chemical …, 2022 - ACS Publications
Dopaminergic pathways control highly consequential aspects of physiology and behavior. One of the most therapeutically important and best-studied receptors in these pathways is …
In 3–5 h at 60–80ºC in pyridine, thiosemicarbazones reacted with 2‐arylidenemalononitriles to afford arylidenehydrazono‐4‐aryl‐2, 3‐dihydrothiazole‐5‐carbonitriles. On repeating the …
R Reinart-Okugbeni, A Vonk, A Uustare… - Bioorganic & medicinal …, 2013 - Elsevier
A novel set of 1-substituted apomorphines as dopaminergic agonists were synthesized according to our new strategy employing the acid-catalyzed rearrangement of diversely …