Xanthates routes to sulfur-containing heterocycles

F Gholami, S Ansari, B Larijani, M Mahdavi - Journal of Organometallic …, 2023 - Elsevier
Sulfur-containing heterocycles, due to their application in material science, biology, and
pharmaceutics, have great importance. Although different sulfurating agents have been …

[PDF][PDF] Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders

N Ye, JL Neumeyer, RJ Baldessarini, X Zhen, A Zhang - Chem. Rev, 2013 - academia.edu
Dopamine (DA) is a critical neurotransmitter in the mammalian central nervous system
(CNS). The cerebral dopaminergic system is implicated in the pathophysiology of several …

Metal-and Catalyst-Free, Formal [4+ 1] Annulation via Tandem C O/C S Functionalization: One-Pot Access to 3, 5-Disubstituted/Annulated Isothiazoles

G Shukla, A Srivastava, MS Singh - Organic letters, 2016 - ACS Publications
An operationally simple and user-friendly new protocol for the synthesis of 3, 5-disubstituted/
annulated isothiazoles is devised utilizing β-ketodithioesters/β-ketothioamides and NH4OAc …

Recent developments in the chemistry of thebaine and its transformation products as pharmacological targets

S Berenyi, C Csutoras, A Sipos - Current medicinal chemistry, 2009 - ingentaconnect.com
The most practical synthetic routes to the preparation of as important pharmaceuticals as
oxycodone, naloxone, naltrexone, nalbuphine and buprenorphine have utilized the alkaloid …

Current state of agonist radioligands for imaging of brain dopamine D2/D3 receptors in vivo with positron emission tomography

S J. Finnema, B Bang-Andersen… - Current topics in …, 2010 - benthamdirect.com
Dopamine (DA) is known to play an important role in numerous brain functions and has
been suggested to be involved in several neuropsychiatric and neurological disorders. From …

Transition Metal‐Free Synthesis of Substituted Isothiazoles via Three‐Component Annulation of Alkynones, Xanthate and NH4I

J Li, J Li, X Ji, Q Liu, L Chen… - Advanced Synthesis & …, 2021 - Wiley Online Library
A protocol was described to access diverse isothiazoles with functionalization potential via
transition metal‐free three‐component annulation of alkynones, potassium ethylxanthate …

Access to 4-substituted isothiazoles through three-component cascade annulation and their application in C–H activation

G Huang, J Li, X Ji, L Chen, Q Liu, X Chen… - Chemical …, 2020 - pubs.rsc.org
The use of potassium ethyl xanthate (EtOCS2k) as a sulfur atom donor enabled the
transition-metal-free [3+ 1+ 1] cascade annulation of isopropene derivatives with NH4I in …

Developing Photoaffinity Probes for Dopamine Receptor D2 to Determine Targets of Parkinson's Disease Drugs

ST Kim, EJ Doukmak, RG Flax, DJ Gray… - ACS Chemical …, 2022 - ACS Publications
Dopaminergic pathways control highly consequential aspects of physiology and behavior.
One of the most therapeutically important and best-studied receptors in these pathways is …

Synthesis of potentially antioxidant and antibacterial biologically active thiazolidines

AA Aly, EA Ishak, T El Malah, AB Brown… - Journal of …, 2015 - Wiley Online Library
In 3–5 h at 60–80ºC in pyridine, thiosemicarbazones reacted with 2‐arylidenemalononitriles
to afford arylidenehydrazono‐4‐aryl‐2, 3‐dihydrothiazole‐5‐carbonitriles. On repeating the …

1-substituted apomorphines as potent dopamine agonists

R Reinart-Okugbeni, A Vonk, A Uustare… - Bioorganic & medicinal …, 2013 - Elsevier
A novel set of 1-substituted apomorphines as dopaminergic agonists were synthesized
according to our new strategy employing the acid-catalyzed rearrangement of diversely …