The role of 'stand-alone'coronary angiography (CAG) in the management of patients with
chronic coronary syndromes is the subject of debate, with arguments for its replacement with …

Coronary artery blood flow is influenced by various factors including vessel geometry,
hemodynamic conditions, timing in the cardiac cycle, and rheological conditions. Multiple …

The E3 ubiquitin ligase HMG-CoA reductase degradation protein 1 (Hrd1) is a key enzyme
for ER-associated degradation of misfolded proteins. Its role in ischemic heart disease has …

Abstract Coronary Artery Disease (CAD) is one of the most common forms of heart disease,
caused by a buildup of atherosclerotic plaque in the coronary arteries. When this buildup is …

Background Invasively measured fractional flow reserve (FFR) and index of microcirculatory
resistance (IMR) are gold standards for the diagnosis of coronary artery disease (CAD) and …

Background: Quantification of coronary blood flow is used to evaluate coronary artery
disease, but our understanding of flow through branched systems is poor. Murray's law …

Background Increased coronary microvascular resistance (CMVR) is associated with
coronary microvascular dysfunction (CMD). Although CMD is more common in women, sex …

Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous
group of conditions that include both atherosclerotic (coronary plaque disruption) and non …

Introduction: Coronary microvascular disease is one of the responsible factors for cardiac
perfusion impairment. Due to diagnostic and treatment challenges, this pathology …

The current management of acute coronary syndromes (ACS) is with an invasive strategy to
guide treatment. However, identifying the lesions which are physiologically significant can …