Nephrotoxicity in the age of immune checkpoint inhibitors: mechanisms, diagnosis, and management

K Moturi, H Sharma, N Hashemi-Sadraei - International Journal of …, 2023 - mdpi.com
Immune checkpoint inhibitors (ICI) revolutionized cancer therapy by augmenting anti-tumor
immunity via cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed death …

Onconephrology 2022: an update

M Bonilla, P Gudsoorkar, R Wanchoo, SM Herrmann… - Kidney360, 2023 - journals.lww.com
Onconephrology is an upcoming and expanding subspecialty that deals with the
intersections between hematology/oncology and nephrology. With the paradigm shift in the …

The renal damage and mechanisms relevant to antitumoral drugs

J Tang, N Yang, S Pan, P Ren, M Chen, J Jin… - Frontiers in …, 2023 - frontiersin.org
Over the past few decades, significant progress has been made in the development of drugs
to combat cancer. It is unfortunate that these drugs can also lead to various kidney injuries …

Immune checkpoints inhibitors and its link to acute kidney injury and renal prognosis

M Kanbay, AB Yildiz, D Siriopol, S Vehbi… - … Urology and Nephrology, 2023 - Springer
Background Immunotherapy with immune checkpoint inhibitors (ICPi) may cause acute
kidney injury (AKI) and their use is increasing. Materials and methods This is a single-center …

Urinary soluble PD-1 as a biomarker of checkpoint inhibitor-induced acute tubulointerstitial nephritis

F Gomez-Preciado, L Martinez-Valenzuela… - Clinical Kidney …, 2024 - academic.oup.com
Background Acute interstitial nephritis (AIN) related to immune checkpoint inhibitors (ICI-
AIN) has a not completely understood pathophysiology. Our objectives were to analyze …

Immunotherapy in oncology and the kidneys: a clinical review of the evaluation and management of kidney immune-related adverse events

A Rao Ullur, G Côté, K Pelletier… - Clinical Kidney …, 2023 - academic.oup.com
Immune checkpoint inhibitors (ICI) are now widely used in the treatment of many cancers,
and currently represent the standard of care for multiple malignancies. These agents …

Cancer drugs and acute kidney injury: new therapies and new challenges

I Gork, F Xiong, A Kitchlu - Current Opinion in Nephrology and …, 2024 - journals.lww.com
Cancer drugs and acute kidney injury: new therapies and new challenges Page 1 MNH 330503
CURRENT OPINION Cancer drugs and acute kidney injury: new therapies and new challenges …

Association of Proton Pump Inhibitor Use and Immune Checkpoint Inhibitor Mediated Acute Kidney Injury: A Meta-Analysis and a Review of Related Outcomes

A Mohan, P Krisanapan, S Tangpanithandee… - American Journal of …, 2024 - karger.com
Abstract Introduction: Immune checkpoint inhibitors (ICIs) have revolutionized cancer
treatment. However, they pose the risk of immune-related adverse events, including ICI …

Development and validation of a nomogram for predicting the occurrence of renal dysfunction after treatment of immune checkpoint inhibitor: a retrospective case …

J Su, P Chen, Y Yang, Z Gao, Z Bi, M Feng - BMJ open, 2024 - bmjopen.bmj.com
Purpose The administration of immune checkpoint inhibitors (ICIs) may lead to renal
adverse events, notably including renal dysfunction. To early predict the probability of renal …

Revisiting the role of acute kidney injury in patients on immune checkpoint inhibitors: a good prognosis renal event with a significant impact on survival

C García-Carro, KD Jhaveri… - Clinical Kidney …, 2023 - academic.oup.com
In the last decade, immune checkpoint inhibitors (ICI) have become a cornerstone in the
treatment of a wide range of malignancies. It is well established that ICI are associated with …