Benzofuran compounds are a class of compounds that are ubiquitous in nature. Numerous
studies have shown that most benzofuran compounds have strong biological activities such …

The nitrile or cyano (–CN) group is one of the most appreciated and effective functional
groups in organic synthesis, having a polar unsaturated C–N triple bond. Despite sufficient …

A general approach for the α-arylation of heteroarenes with nitroarenes via denitrative
coupling is reported for the first time. Various heteroarenes, including derivatives of furan …

Excess accumulation of amyloid‐β (Aβ) protein in the brain is the primary pathogenesis of
Alzheimer's disease (AD). Inhibition of Aβ fibrillation and disaggregation of Aβ fibrils is an …

Herein, we report a series of selective sub-nanomolar inhibitors against
butyrylcholinesterase (BChE). These compounds, bearing a novel N-benzyl benzamide …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is difficult to treat.
Extracellular amyloid is the principal pathological criterion for the diagnosis of AD. Amyloid β …

Inhibition of α-glucosidase is one of the important approaches in designing antidiabetic
drugs for its role in decrease of the carbohydrates digestion to avoid post-prandial increase …

Introduction: Benzofuran is a fundamental unit in numerous bioactive heterocycles. They
have attracted chemists and medical researchers due to their broad range of biological …

Herein, the benzofuran-based hydrazones derivatives such as N'-(1-(benzofuran-2-yl)
ethylidene) isonicotinohydrazide (BEINH), N'-(1-(benzofuran-2-yl) ethylidene) nicotine …

Butyrylcholinesterase (BChE) is a promising biomarker and effective therapeutic target for
Alzheimer's disease (AD). Herein, we designed a BChE-activated near-infrared (NIR) probe …