Incidence and impact of resistance against approved antiretroviral drugs

D Pillay, S Taylor, DD Richman - Reviews in Medical Virology, 2000 - Wiley Online Library
More than 15 antiretroviral drugs are now available for clinical use, and have led to
significant reductions in morbidity and mortality for HIV infected individuals. Nevertheless …

UK Guideline for the use of post-exposure prophylaxis for HIV following sexual exposure

M Fisher, P Benn, B Evans, A Pozniak… - … journal of STD & …, 2006 - journals.sagepub.com
We present the British Association for Sexual Health and HIV (BASHH) guidelines for post-
exposure prophylaxis after sexual exposure (PEPSE) to HIV. This document includes a …

Antiretroviral drug resistance testing in adult HIV-1 infection: recommendations of an International AIDS Society–USA Panel

MS Hirsch, F Brun-Vézinet, TD Richard, SM Hammer… - Jama, 2000 - jamanetwork.com
ObjectiveAssays for drug resistance testing in human immunodeficiency virus type 1 (HIV-1)
infection are now available and clinical studies suggest that viral drug resistance is …

The emergence and epidemiology of resistance in the nucleoside-experienced HIV-infected population

D Pillay - Antiviral therapy, 2001 - journals.sagepub.com
HIV drug resistance remains one of the most important influences on long-term therapeutic
prospects. Resistance and therapeutic failure arises out of the selection and preservation of …

Prevalence of primary resistance to zidovudine and lamivudine in drug‐naive human immunodeficiency virus type‐1 infected patients: High proportion of reverse …

MA Trabaud, K Leriche‐Guerin, C Regis… - Journal of medical …, 2000 - Wiley Online Library
The presence of primary zidovudine (AZT)‐resistance (mutation T215Y/F) or lamivudine
(3TC)‐resistance (mutation M184V) was evaluated in 90 drug‐naive patients infected with …

Low prevalence of antiretroviral drug resistance among HIV-1 seroconverters in London, 1984–1991

PJ Easterbrook, K Hertogs, A Waters, B Wills… - Journal of Infection, 2002 - Elsevier
Objectives: To examine the prevalence of resistance mutations and natural polymorphisms
to reverse transcriptase (RT) and protease inhibitors in a cohort of patients with defined …

[图书][B] Nucleic acid sequence-based amplification: Relative performance and applications in HIV-1 disease monitoring and patient management

LC Dann - 2002 - search.proquest.com
In recent years there have been significant advances in the understanding of the
pathogenesis of HIV-1 infection. Central to this progress has been the development of …

[引用][C] 成人のHIV-1 感染症における抗レトロウイルス薬の耐性試験

MS Hirsch, F Brun-Vezinet, RT D'Aquila, DR Kuritzkes