P La Rosée, AC Horne, M Hines… - Blood, The Journal …, 2019 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) …
G Goyal, A Tazi, RS Go, KL Rech… - Blood, The Journal …, 2022 - ashpublications.org
Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary …
Bone tumors are a rare and heterogeneous group of neoplasms that occur in the bone. The diversity and considerable morphologic overlap of bone tumors with other mesenchymal …
G Goyal, ML Heaney, M Collin… - Blood, The Journal …, 2020 - ashpublications.org
Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK …
O Abla, E Jacobsen, J Picarsic… - Blood, The Journal …, 2018 - ashpublications.org
Abstract Rosai-Dorfman-Destombes disease (RDD) is a rare non–Langerhans cell histiocytosis characterized by accumulation of activated histiocytes within affected tissues …
E Bergsten, AC Horne, M Aricó… - Blood, The Journal …, 2017 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome comprising familial/genetic HLH (FHL) and secondary HLH. In the HLH-94 study …
KL McClain, C Bigenwald, M Collin… - Nature Reviews …, 2021 - nature.com
The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for diseases characterized by pathogenic myeloid cells that share histological features with …
C Rodriguez-Galindo, CE Allen - Blood, The Journal of the …, 2020 - ashpublications.org
Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …
G Griffin, S Shenoi, GC Hughes - Best Practice & Research Clinical …, 2020 - Elsevier
Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening state of immune hyperactivation that arises in the setting of genetic mutations and infectious, inflammatory, or …