Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

At the time of implantation, the trophoblast cells of the embryo adhere and then invade into
the maternal endometrium and eventually establish placentation. The endometrium at the …

Cells must alter their expression profiles and morphological characteristics but also reshape
the extracellular matrix (ECM) to fulfill their functions throughout their lifespan. Matrix …

BACKGROUND During pregnancy, maternal uterine spiral arteries (SAs) are remodelled
from minimal-flow, high-resistance vessels into larger diameter vessels with low resistance …

The transformation of cytotrophoblast (CTB) to extravillous trophoblast (EVT) is an essential
process for placental implantation. EVT generated at the tips of the anchoring villi migrate …

A number of important changes take place in the maternal uterine vasculature during the first
few weeks of pregnancy resulting in increased blood flow to the intervillous space. Vascular …

Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade various
components of the extracellular matrix (ECM). MMPs could also regulate the activity of …

Pregnancy success is determined by a complex progress that includes trophoblast invasion
and placentation. Matrix metalloproteinases (MMPs) and tissue inhibitors of …

In addition to its role in the prevention of neural tube defects, folic acid has many other
physiological functions, including cell proliferation, DNA replication, and antioxidant …