W Wang, S Nag, X Zhang, MH Wang… - Medicinal research …, 2015 - Wiley Online Library
Ribosomes are essential components of the protein synthesis machinery. The process of ribosome biogenesis is well organized and tightly regulated. Recent studies have shown …
B Deng, W Kong, X Shen, C Han, Z Zhao… - Journal of Translational …, 2024 - Springer
Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common organelle existing in most mammal cells, and its complex and dynamic functions in …
Mitochondria are prominently understood as power houses producing ATP the primary energy currency of the cell. However, mitochondria are also known to play an important role …
Stemness encompasses the capability of a cell for self-renewal and differentiation. The stem cell maintains a balance between proliferation, quiescence, and regeneration via …
Dysregulation of lipid metabolism is pathologically associated to metabolic diseases such as atherogenic dyslipidemia, hepatic steatosis, obesity and type 2 diabetes. Up-regulation of …
Endometrial cancer (EC) is one of the most frequent causes of cancer death among women in developed countries. Histopathological diagnosis and imaging techniques for EC are …
M Mushtaq, HV Gaza, EV Kashuba - Advances in cancer research, 2016 - Elsevier
Human retinoblastoma gene RB1 is the first tumor suppressor gene (TSG) isolated by positional cloning in 1986. RB is extensively studied for its ability to regulate cell cycle by …
M Mushtaq, L Jensen, S Davidsson, OV Grygoruk… - Scientific Reports, 2018 - nature.com
We have earlier found abnormal expression of the mitochondrial ribosomal protein S18-2 (MRPS18-2, S18-2) in endometrial cancer, compared to the expression in hyperplasia and …
Estrogen receptors α (ER‐α) and β (ER‐β) play distinct biological roles in onset and progression of hormone‐responsive breast cancer, with ER‐β exerting a modulatory activity …