Antimicrobial properties of equine stromal cells and platelets and future directions

LM Pezzanite, L Chow, SW Dow… - Veterinary Clinics …, 2023 - vetequine.theclinics.com
Increasing antimicrobial resistance in veterinary practice has driven the investigation of
novel therapeutic strategies including regenerative and biologic therapies to treat bacterial …

Preclinical Evidence for the Use of Oral Mesenchymal Stem Cell-Derived Extracellular Vesicles in Bone Regenerative Therapy: A Systematic Review

A Olaechea, K Benabdellah… - Stem Cells …, 2023 - academic.oup.com
The development of extracellular vesicles (EVs) therapies has revolutionized personalized
medicine, opening up new possibilities for treatment. EVs have emerged as a promising …

Mesenchymal stem cell conditioned medium modulates inflammation in tenocytes: complete conditioned medium has superior therapeutic efficacy than its …

R Soukup, I Gerner, T Mohr, S Gueltekin… - International Journal of …, 2023 - mdpi.com
Tendinopathy, a prevalent overuse injury, lacks effective treatment options, leading to a
significant impact on quality of life and socioeconomic burden. Mesenchymal stem/stromal …

[HTML][HTML] Therapeutic application of extracellular vesicles derived from mesenchymal stem cells in domestic animals

A Lanci, E Iacono, B Merlo - Animals, 2024 - mdpi.com
Simple Summary Extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs)
have recently been described in human and veterinary medicine and great interest is …

Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer: proof-of-principle

J Steenbrugge, G Pauwelyn, K Demeyere… - Frontiers in …, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) remains difficult to treat, especially due to ineffective
immune responses. Current treatments mainly aim at a cytotoxic effect, whereas (stem) cell …

Equine mesenchymal stem cell derived extracellular vesicle immunopathology biomarker discovery

DE Reynolds, P Vallapureddy… - Journal of …, 2023 - Wiley Online Library
The use of mesenchymal stem cells (MSCs) in human and veterinary clinical applications
has become a subject of increasing importance due to their roles in immunomodulation and …

[图书][B] Use of Biologic and Regenerative Therapies in Equine Practice, An Issue of Veterinary Clinics of North America: Equine Practice, E-Book

LV Schnabel - 2023 - books.google.com
In this issue of Veterinary Clinics of North America: Equine Practice, guest editor Ds. Lauren
V. Schnabel brings her considerable expertise to the topic of Use of Biologic and …

Investigating the Small Non-coding RNA Profile in Equine Osteoarthritis

C Castanheira - 2024 - livrepository.liverpool.ac.uk
One of the biggest challenges for equine medicine is the frequent occurrence of joint
diseases, which are responsible for wastage of horses across all equestrian disciplines …

[HTML][HTML] Equine mesenchymal stem cell–derived extracellular vesicle productivity but not overall yield is improved via 3-D culture with chemically defined media

AM Gaesser, AIJ Usimaki, DA Barot… - Journal of the …, 2024 - Am Vet Med Assoc
OBJECTIVE Mesenchymal stem cell (MSC) extracellular vesicles (EVs) have emerged as a
biotherapeutic for osteoarthritis; however, manufacturing large quantities is not practical …