[HTML][HTML] Xanthine oxidoreductase: One enzyme for multiple physiological tasks

M Bortolotti, L Polito, MG Battelli, A Bolognesi - Redox biology, 2021 - Elsevier
Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from
a complicated evolutionary process that assigned it many physiological roles. The main …

Nitrate reductase regulates plant nitric oxide homeostasis

A Chamizo-Ampudia, E Sanz-Luque, A Llamas… - Trends in plant …, 2017 - cell.com
Nitrate reductase (NR) is a key enzyme for nitrogen acquisition by plants, algae, yeasts, and
fungi. Nitrate, its main substrate, is required for signaling and is widely distributed in diverse …

Xanthine oxidoreductase‐derived reactive species: physiological and pathological effects

MG Battelli, L Polito, M Bortolotti… - Oxidative medicine and …, 2016 - Wiley Online Library
Xanthine oxidoreductase (XOR) is the enzyme that catalyzes the oxidation of hypoxanthine
to xanthine and xanthine to uric acid and is widely distributed among species. In addition to …

[HTML][HTML] The role of xanthine oxidoreductase and uric acid in metabolic syndrome

MG Battelli, M Bortolotti, L Polito, A Bolognesi - Biochimica et Biophysica …, 2018 - Elsevier
Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …

[HTML][HTML] Purinergic signaling in the modulation of redox biology

LEB Savio, R Leite-Aguiar, VS Alves, R Coutinho-Silva… - Redox Biology, 2021 - Elsevier
Purinergic signaling is a cell communication pathway mediated by extracellular nucleotides
and nucleosides. Tri-and diphosphonucleotides are released in physiological and …

Nitric oxide‐mediated regulation of oxidative stress in plants under metal stress: a review on molecular and biochemical aspects

A Sharma, C Soares, B Sousa, M Martins… - Physiologia …, 2020 - Wiley Online Library
Given their sessile nature, plants continuously face unfavorable conditions throughout their
life cycle, including water scarcity, extreme temperatures and soil pollution. Among all, metal …

[HTML][HTML] Xanthine oxidoreductase-catalyzed reactive species generation: a process in critical need of reevaluation

N Cantu-Medellin, EE Kelley - Redox biology, 2013 - Elsevier
Nearly 30 years have passed since the discovery of xanthine oxidoreductase (XOR) as a
critical source of reactive species in ischemia/reperfusion injury. Since then, numerous …

Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency

A Lichota, L Gwozdzinski, K Gwozdzinski - European Journal of Medicinal …, 2019 - Elsevier
The term varicose vein refers to the twisted and swollen vein visible under the skin surface
which occurs most commonly in the leg. Epidemiological studies report a varying …

[HTML][HTML] Breathing new life into nitric oxide signaling: a brief overview of the interplay between oxygen and nitric oxide

DD Thomas - Redox biology, 2015 - Elsevier
Nitric oxide (• NO, nitrogen monoxide) is one of the most unique biological signaling
molecules associated with a multitude of physiologic and pathological conditions. In order to …

A dual system formed by the ARC and NR molybdoenzymes mediates nitrite‐dependent NO production in Chlamydomonas

A Chamizo‐Ampudia, E Sanz‐Luque… - Plant, Cell & …, 2016 - Wiley Online Library
Nitric oxide (NO) is a relevant signal molecule involved in many plant processes. However,
the mechanisms and proteins responsible for its synthesis are scarcely known. In most …