The epidemiology of carbapenemases in Latin America and the Caribbean

K Escandón-Vargas, S Reyes, S Gutiérrez… - Expert review of anti …, 2017 - Taylor & Francis
ABSTRACT Introduction: Enterobacteriaceae, Pseudomonas spp., and Acinetobacter spp.
infections are major causes of morbidity and mortality, especially due to the emergence and …

Antimicrobial resistance among Enterobacteriaceae in South America: history, current dissemination status and associated socioeconomic factors

RR Bonelli, BM Moreira, RC Picão - Drug Resistance Updates, 2014 - Elsevier
South America exhibits some of the higher rates of antimicrobial resistance in
Enterobactericeae worldwide. This continent includes 12 independent countries with huge …

[HTML][HTML] Distribución y caracterización molecular de betalactamasas en bacterias Gram negativas en Colombia, 2001-2016

AM Rada, C Hernández-Gómez, E Restrepo… - Biomédica, 2019 - scielo.org.co
Las betalactamasas, enzimas con capacidad hidrolítica frente a los antibióticos
betalactámicos, son responsables del principal mecanismo de resistencia en bacterias …

Complexity of Genomic Epidemiology of Carbapenem-Resistant Klebsiella pneumoniae Isolates in Colombia Urges the Reinforcement of Whole Genome …

SY Saavedra, JF Bernal… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an emerging
public health problem. This study explores the specifics of CRKP epidemiology in Colombia …

Bogotá River anthropogenic contamination alters microbial communities and promotes spread of antibiotic resistance genes

CE Posada-Perlaza, A Ramírez-Rojas, P Porras… - Scientific reports, 2019 - nature.com
The increase in antibiotic resistant bacteria has raised global concern regarding the future
effectiveness of antibiotics. Human activities that influence microbial communities and …

Clinical characteristics of carbapenem-resistant Klebsiella pneumoniae infections in ill and colonized children in Colombia

A Díaz, DC Ortiz, M Trujillo, C Garcés… - The Pediatric …, 2016 - journals.lww.com
Background: Multidrug-resistant Gram-negative infections represent a growing problem and
a serious global threat. Data in children are scarce. Klebsiella pneumoniae …

Genetic analysis of carbapenemase-producing Gram-negative bacteria isolated from a university teaching hospital in Egypt

AM Soliman, HO Zarad, H Nariya, T Shimamoto… - Infection, Genetics and …, 2020 - Elsevier
A total of 65 non-replicate Gram-negative bacterial strains were recovered from clinical
specimens between April and September 2014 at a University Hospital in Egypt. This …

[HTML][HTML] Emergence and spread of VIM-type metallo-β-lactamase-producing Pseudomonas aeruginosa clinical isolates in Japan

T Hishinuma, H Uchida, M Tohya, M Shimojima… - Journal of Global …, 2020 - Elsevier
Objectives The aim of this study was to determine the genetic and epidemiological
properties of Pseudomonas aeruginosa strains producing VIM-type metallo-β-lactamases …

[HTML][HTML] Epidemiology of carbapenemase-producing Enterobacteriaceae in a pediatric hospital in a country with high endemicity

E Castagnola, P Tatarelli, A Mesini, I Baldelli… - Journal of infection and …, 2019 - Elsevier
Background Little is known about epidemiology of carbapenemase-producing
Enterobacteriaceae (CPE) in children. Aim of this study was to describe CPE epidemiology …

Exploring the role of residue 228 in substrate and inhibitor recognition by VIM metallo-β-lactamases

MF Mojica, SG Mahler, CR Bethel, MA Taracila… - Biochemistry, 2015 - ACS Publications
β-Lactamase inhibitors (BLIs) restore the efficacy of otherwise obsolete β-lactams. However,
commercially available BLIs are not effective against metallo-β-lactamases (MBLs), which …