[HTML][HTML] Advancing application of mesenchymal stem cell-based bone tissue regeneration

F Shang, Y Yu, S Liu, L Ming, Y Zhang, Z Zhou, J Zhao… - Bioactive materials, 2021 - Elsevier
Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …

Advancing biomaterials of human origin for tissue engineering

FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Current trends and future perspectives of bone substitute materials–from space holders to innovative biomaterials

A Kolk, J Handschel, W Drescher, D Rothamel… - Journal of Cranio …, 2012 - Elsevier
An autologous bone graft is still the ideal material for the repair of craniofacial defects, but its
availability is limited and harvesting can be associated with complications. Bone …

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs)

H Cheng, W Jiang, FM Phillips, RC Haydon, Y Peng… - Jbjs, 2003 - journals.lww.com
Background: Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and
clinical trials are currently underway to evaluate the ability of certain BMPs to promote …

[HTML][HTML] BMP signaling in mesenchymal stem cell differentiation and bone formation

M Beederman, JD Lamplot, G Nan, J Wang… - Journal of biomedical …, 2013 - ncbi.nlm.nih.gov
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and have
diverse functions during development and organogenesis. BMPs play a major role in …

Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery

Q Kang, MH Sun, H Cheng, Y Peng, AG Montag… - Gene therapy, 2004 - nature.com
Efficacious bone regeneration could revolutionize the clinical management of bone and
musculoskeletal disorders. Although several bone morphogenetic proteins (BMPs)(mostly …

Injectable biomaterials for regenerating complex craniofacial tissues

JD Kretlow, S Young, L Klouda, M Wong… - Advanced …, 2009 - Wiley Online Library
Engineering complex tissues requires a precisely formulated combination of cells,
spatiotemporally released bioactive factors, and a specialized scaffold support system …

[HTML][HTML] BMP9 signaling in stem cell differentiation and osteogenesis

JD Lamplot, J Qin, G Nan, J Wang, X Liu… - American journal of …, 2013 - ncbi.nlm.nih.gov
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily and play a
critical role in skeletal development, bone formation and stem cell differentiation. Disruptions …

Local drug delivery for enhancing fracture healing in osteoporotic bone

L Kyllönen, M D'Este, M Alini, D Eglin - Acta biomaterialia, 2015 - Elsevier
Fragility fractures can cause significant morbidity and mortality in patients with osteoporosis
and inflict a considerable medical and socioeconomic burden. Moreover, treatment of an …

3D-printed ceramic bone scaffolds with variable pore architectures

HK Lim, SJ Hong, SJ Byeon, SM Chung… - International Journal of …, 2020 - mdpi.com
This study evaluated the mechanical properties and bone regeneration ability of 3D-printed
pure hydroxyapatite (HA)/tricalcium phosphate (TCP) pure ceramic scaffolds with variable …