Process of inflammation and complex interactions between immune and cancer cells within
tumor microenvironment are known to drive and shape the outcome of the neoplastic …

In this review, we discuss the importance of capsaicin to the current understanding of
neuronal modulation of pain and explore the mechanisms of capsaicin-induced pain. We …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Abstract Purpose of Review Vaping is gaining popularity in the USA, particularly among
teens and young adults. While e-cigs are commonly represented as safer alternatives to …

Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

Lung nociceptors initiate cough and bronchoconstriction. To elucidate if these fibers also
contribute to allergic airway inflammation, we stimulated lung nociceptors with capsaicin and …

Atopic dermatitis (AD) is a multifaceted, chronic relapsing inflammatory skin disease that
affects people of all ages. It is characterized by chronic eczema, constant pruritus, and …

Transient receptor potential vanilloid subtype 1 (TRPV1), a member of the transient receptor
potential vanilloid (TRPV) channel family, is a nonselective cation channel that is widely …

Over the last few decades, there has been an explosion of scientific publications reporting
the many and varied roles of transient receptor potential (TRP) ion channels in physiological …

Capsaicin, the pungent ingredient of chili peppers, displays potent anti-neoplastic activity in
a wide array of human cancer cells. The present manuscript examines the signaling …