[HTML][HTML] Protective non-neutralizing SARS-CoV-2 monoclonal antibodies
A Izadi, P Nordenfelt - Trends in immunology, 2024 - cell.com
Recent studies show an important role for non-neutralizing anti-spike antibodies, including
monoclonal antibodies (mAbs), in robustly protecting against SARS-CoV-2 infection. These …
monoclonal antibodies (mAbs), in robustly protecting against SARS-CoV-2 infection. These …
Stellabody: A novel hexamer‐promoting mutation for improved IgG potency
CA Whitehead, BD Wines, AM Davies… - Immunological …, 2024 - Wiley Online Library
Advances in antibody engineering are being directed at the development of next generation
immunotherapeutics with improved potency. Hexamerisation of IgG is a normal …
immunotherapeutics with improved potency. Hexamerisation of IgG is a normal …
[HTML][HTML] Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches
V Ovcinnikovs, K Dijkman, GG Zom, FJ Beurskens… - Seminars in …, 2025 - Elsevier
The complement system plays an integral role in both innate and adaptive immune
responses. Beyond its protective function against infections, complement is also known to …
responses. Beyond its protective function against infections, complement is also known to …
Protective Non-neutralizing anti–N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA. 2.86-JN. 1 with Superfluous In Vivo …
A Izadi, M Godzwon, A Söderlund Strand… - The Journal of …, 2024 - journals.aai.org
Substantial evidence supports that Fc-mediated effector functions of anti-spike Abs
contribute to anti–SARS-Cov-2 protection. We have previously shown that two non …
contribute to anti–SARS-Cov-2 protection. We have previously shown that two non …