Mechanism of METTL3‐mediated m6A modification in depression‐induced cognitive deficits
J Niu, B Wang, T Wang, T Zhou - American Journal of Medical …, 2022 - Wiley Online Library
Depressive disorder (DD) is associated with N6‐methyladenosine (m6A) hypermethylation.
This study sought to explore the molecular mechanism of Methyltransferase‐like 3 (METTL3) …
This study sought to explore the molecular mechanism of Methyltransferase‐like 3 (METTL3) …
Functional analysis of epilepsy‐associated GABAA receptor mutations using Caenorhabditis elegans
A Gadhia, E Barker, A Morgan, JW Barclay - Epilepsia Open, 2024 - Wiley Online Library
Objective GABAA receptor subunit mutations pose a significant risk for genetic generalized
epilepsy; however, there are over 150 identified variants, many with unknown or unvalidated …
epilepsy; however, there are over 150 identified variants, many with unknown or unvalidated …
Drug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure
JR Polli, DL Dobbins, RA Kobet, MA Farwell, B Zhang… - Neurotoxicology, 2015 - Elsevier
Nicotine, the major psychoactive compound in tobacco, targets nicotinic acetylcholine
receptors (nAChRs) and results in drug dependence. The nematode Caenorhabditis …
receptors (nAChRs) and results in drug dependence. The nematode Caenorhabditis …
Behavior of Caenorhabditis elegans in a nicotine gradient modulated by food
R Sobkowiak, P Kaczmarek, M Kowalski… - Drug and Chemical …, 2019 - Taylor & Francis
Nicotine decreases food intake, and smokers often report that they smoke to control their
weight. To see whether similar phenomena could be observed in the model organism …
weight. To see whether similar phenomena could be observed in the model organism …
Effects of Environmental Sample Forms on Toxicity Induction
D Wang, D Wang - Exposure Toxicology in Caenorhabditis elegans, 2020 - Springer
The sensitive property and potential to assess long-term effect have made Caenorhabditis
elegans as a powerful animal model to perform the safety evaluation of different forms of …
elegans as a powerful animal model to perform the safety evaluation of different forms of …
Caenorhabditis elegans as an emerging model for studying the basic biology of anorectic effects of nicotine
R Sobkowiak, P Kaczmarek, M Kowalski, R Kabaciński… - bioRxiv, 2017 - biorxiv.org
Nicotine decreases food intake, and smokers often report that they smoke to control their
weight. To see whether similar phenomena could be observed in the model organism …
weight. To see whether similar phenomena could be observed in the model organism …