Near-infrared fluorescent probes in cancer imaging and therapy: an emerging field

X Yi, F Wang, W Qin, X Yang, J Yuan - International Journal of …, 2014 - Taylor & Francis
Near-infrared fluorescence (NIRF) imaging is an attractive modality for early cancer
detection with high sensitivity and multi-detection capability. Due to convenient modification …

Research progress of near-infrared fluorescence probes based on indole heptamethine cyanine dyes in vivo and in vitro

C Sun, W Du, B Wang, B Dong, B Wang - BMC chemistry, 2020 - Springer
Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides
numerous advantages for the real-time in vivo monitoring of biological information in living …

In Vivo Targeted Deep-Tissue Photodynamic Therapy Based on Near-Infrared Light Triggered Upconversion Nanoconstruct

S Cui, D Yin, Y Chen, Y Di, H Chen, Y Ma, S Achilefu… - ACS …, 2013 - ACS Publications
Two major challenges of current photodynamic therapy (PDT) are the limited tissue
penetration of excitation light and poor tumor-selectivity of the photosensitizer (PS). To …

Folate-modified gold nanoclusters as near-infrared fluorescent probes for tumor imaging and therapy

H Chen, S Li, B Li, X Ren, S Li, DM Mahounga, S Cui… - Nanoscale, 2012 - pubs.rsc.org
Ultra-small gold nanoclusters (Au NCs) are highly promising materials for tumor imaging
and therapy because of their low toxicity, intrinsic fluorescence, and the availability of …

Multifunctional near-infrared-emitting nano-conjugates based on gold clusters for tumor imaging and therapy

H Chen, B Li, X Ren, S Li, Y Ma, S Cui, Y Gu - Biomaterials, 2012 - Elsevier
Gold nanoclusters (NCs) were functionalized as a fluorescent probe and a pro-drug
intended for tumor diagnosis and therapy. Firstly, Au NCs were conjugated with methionine …

Targeted cancer therapy with a 2-deoxyglucose–based adriamycin complex

J Cao, S Cui, S Li, C Du, J Tian, S Wan, Z Qian, Y Gu… - Cancer research, 2013 - AACR
Adriamycin (ADM) has been effective against many types of solid tumors in clinical
applications. However, its use is limited because of systemic toxicities, primarily …

pH-responsive hybrid quantum dots for targeting hypoxic tumor siRNA delivery

HY Zhu, SY Zhang, Y Ling, GL Meng, Y Yang… - Journal of Controlled …, 2015 - Elsevier
Hypoxia is a characteristic of cancer and plays a key role in tumorigenesis, angiogenesis
and resistance to cancer therapies. SiRNA treatment is effective against hypoxic tumors by …

[HTML][HTML] Optical imaging probes in oncology

C Martelli, AL Dico, C Diceglie, G Lucignani… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer is a complex disease, characterized by alteration of different physiological molecular
processes and cellular features. Keeping this in mind, the possibility of early identification …

Biocompatible gold nanoclusters: synthetic strategies and biomedical prospects

G Zuber, E Weiss, M Chiper - Nanotechnology, 2019 - iopscience.iop.org
The latest advances concerning ultra-small gold nanoparticles (≤ 2 nm) commonly known
as gold nanoclusters (AuNCs) are reviewed and discussed in the context of biological and …

Pegylated drug delivery systems: from design to biomedical applications

F Liu, Y Sun, C Kang, H Zhu - Nano Life, 2016 - World Scientific
Pegylation, as a simple procedure to attach hydrophilic polyethylene glycol (PEG) onto
therapeutic molecule or drug carriers has been utilized widely to deliver small molecules …