Less label, more free: approaches in label‐free quantitative mass spectrometry
In this review we examine techniques, software, and statistical analyses used in label‐free
quantitative proteomics studies for area under the curve and spectral counting approaches …
quantitative proteomics studies for area under the curve and spectral counting approaches …
[PDF][PDF] Integrative physiology of fasting
Extended bouts of fasting are ingrained in the ecology of many organisms, characterizing
aspects of reproduction, development, hibernation, estivation, migration, and infrequent …
aspects of reproduction, development, hibernation, estivation, migration, and infrequent …
Hibernation in black bears: independence of metabolic suppression from body temperature
Black bears hibernate for 5 to 7 months a year and, during this time, do not eat, drink,
urinate, or defecate. We measured metabolic rate and body temperature in hibernating black …
urinate, or defecate. We measured metabolic rate and body temperature in hibernating black …
Metabolic rate depression: the biochemistry of mammalian hibernation
During winter hibernation, small mammals fall into long periods of deep cold torpor where
metabolic rate is suppressed by> 90% and core body temperature can fall to near 0 C …
metabolic rate is suppressed by> 90% and core body temperature can fall to near 0 C …
Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California
The influence of seasons on biological processes is poorly understood. In order to identify
biological seasonal patterns based on diverse molecular data, rather than calendar dates …
biological seasonal patterns based on diverse molecular data, rather than calendar dates …
Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus)
Background Hibernation is an adaptive strategy to survive in highly seasonal or
unpredictable environments. The molecular and genetic basis of hibernation physiology in …
unpredictable environments. The molecular and genetic basis of hibernation physiology in …
iTRAQ-based quantitative proteomic analysis of Takifugu fasciatus liver in response to low-temperature stress
X Wen, X Zhang, Y Hu, J Xu, T Wang, S Yin - Journal of proteomics, 2019 - Elsevier
Low temperatures profoundly influence the physiological and behavioural processes of
ectotherms, especially teleosts, which have made them the subjects of strong interest over …
ectotherms, especially teleosts, which have made them the subjects of strong interest over …
Maternal nutrition modulates fetal development by inducing placental efficiency changes in gilts
L Che, ZG Yang, MM Xu, SY Xu, LQ Che, Y Lin… - BMC genomics, 2017 - Springer
Background Intra-uterine growth restriction (IUGR) and fetal overgrowth increase risks to
postnatal health. Maternal nutrition is the major intrauterine environmental factor that alters …
postnatal health. Maternal nutrition is the major intrauterine environmental factor that alters …
Examining the practical limits of batch effect-correction algorithms: When should you care about batch effects?
Batch effects are technical sources of variation and can confound analysis. While many
performance ranking exercises have been conducted to establish the best batch effect …
performance ranking exercises have been conducted to establish the best batch effect …
Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia
Y Lee, KR Johnson, JM Hallenbeck - 2012 - journals.plos.org
Hibernation torpor provides an excellent model of natural tolerance to ischemia. We have
previously shown that massive global SUMOylation occurs during hibernation torpor in …
previously shown that massive global SUMOylation occurs during hibernation torpor in …