Strategies and tools for studying the metabolism and function of γ-aminobutyrate in plants. I. Pathway structure

BJ Shelp, GG Bozzo, CP Trobacher, G Chiu… - Botany, 2012 - cdnsciencepub.com
γ-Aminobutyrate (GABA) is a ubiquitous four-C, nonprotein, amino acid that has been linked
to stress, signaling, and storage in plants. In this paper, we discuss analytical, enzyme …

Succinic semialdehyde dehydrogenase: biochemical–molecular–clinical disease mechanisms, redox regulation, and functional significance

KJ Kim, PL Pearl, K Jensen, OC Snead… - Antioxidants & redox …, 2011 - liebertpub.com
Succinic semialdehyde dehydrogenase (SSADH; aldehyde dehydrogenase 5a1, ALDH5A1;
EC 1.2. 1.24; OMIM 610045, 271980) deficiency is a rare heritable disorder that disrupts the …

Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species

AG Hettle, JK Hobbs, B Pluvinage, C Vickers… - Communications …, 2019 - nature.com
Pseudoalteromonas is a globally distributed marine-associated genus that can be found in a
broad range of aquatic environments, including in association with macroalgal surfaces …

Adaptive laboratory evolution accelerated glutarate production by Corynebacterium glutamicum

C Prell, T Busche, C Rückert, L Nolte… - Microbial Cell …, 2021 - Springer
Background The demand for biobased polymers is increasing steadily worldwide. Microbial
hosts for production of their monomeric precursors such as glutarate are developed. To meet …

Biochemical and structural elucidation of the L-carnitine degradation pathway of the human pathogen Acinetobacter baumannii

F Piskol, P Lukat, L Kaufhold, A Heger… - Frontiers in …, 2024 - frontiersin.org
Acinetobacter baumannii is an opportunistic human pathogen which can use host-derived L-
carnitine as sole carbon and energy source. Recently, an L-carnitine transporter (Aci1347) …

Gene replacement therapies for inherited disorders of neurotransmission: Current progress in succinic semialdehyde dehydrogenase deficiency

HHC Lee, IT Latzer, M Bertoldi, G Gao… - Journal of Inherited …, 2024 - Wiley Online Library
Neurodevelopment is a highly organized and complex process involving lasting and often
irreversible changes in the central nervous system. Inherited disorders of neurotransmission …

Silver (i) metal–organic framework-embedded polylactic acid electrospun fibrous membranes for efficient inhibition of bacteria

S Zhang, X Ma, H Yu, X Lu, J Liu, L Zhang… - Dalton …, 2022 - pubs.rsc.org
With recent outbreaks of fatal strains of diseases and the emergency of antibiotic resistance,
there is a pressing demand to discover bactericidal materials that can effectively reduce or …

Reduction of mitochondrial protein mitoNEET [2Fe–2S] clusters by human glutathione reductase

AP Landry, Z Cheng, H Ding - Free Radical Biology and Medicine, 2015 - Elsevier
The human mitochondrial outer membrane protein mitoNEET is a newly discovered target of
the type 2 diabetes drug pioglitazone. Structurally, mitoNEET is a homodimer with each …

Structural determinants of substrate specificity in aldehyde dehydrogenases

H Riveros-Rosas, L González-Segura… - Chemico-biological …, 2013 - Elsevier
Within the aldehyde dehydrogenase (ALDH) superfamily, proteins belonging to the ALDH9,
ALDH10, ALDH25, ALDH26 and ALDH27 families display activity as ω-aminoaldehyde …

Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum

J Li, M Sharma, R Meek, A Alhifthi, Z Armstrong… - Chemical …, 2023 - pubs.rsc.org
Sulfolactate (SL) is a short-chain organosulfonate that is an important reservoir of sulfur in
the biosphere. SL is produced by oxidation of sulfolactaldehyde (SLA), which in turn derives …