The developmental and epileptic encephalopathies encompass a group of rare syndromes
characterised by severe drug-resistant epilepsy with onset in childhood and significant …

Management of paediatric epilepsies poses unique challenges around diagnosis, treatment
options, comorbidities and the potential for these factors to interact with processes in the …

Objective The efficacy of perampanel (PER) in pediatric epilepsy with specific etiologies has
not been well established. Here, we investigated outcome and predictors of PER treatment …

Genetic factors contribute to the aetiology of epilepsy in> 50% of cases, and information on
the use of antiseizure medications in people with specific aetiologies will help guide …

Objective Perampanel (PER) is a novel antiepileptic drug. The efficacy, tolerability and
safety of PER in children and adolescents with epilepsy are still unclear. We aimed to study …

Seizures in patients with developmental and epileptic encephalopathies (DEEs) are often
highly resistant to various antiseizure medications. Perampanel (PER) is a novel antiseizure …

Background No interventional study has been conducted in China to assess efficacy and
safety of perampanel in treating Chinese patients with epilepsy, nor has there been any …

Sodium channelopathies are genetic disorders caused by mutations in genes, including
sodium voltage-gated channel alpha subunit 1 (SCN1A), that lead to several epilepsy …