Mathematical models and computer simulations have the great potential to substantially
increase our understanding of the biophysical behavior of the neuromuscular system. This …

The presented chemo-electro-mechanical skeletal muscle model relies on a continuum-
mechanical formulation describing the muscle's deformation and force generation on the …

Biomechanical models and simulations of musculoskeletal function rely on accurate muscle
parameters, such as muscle masses and lines of action, to estimate force production …

Vastus medialis (VM) has two partitions, longus (VML), and obliquus (VMO), which have
been implicated in knee pathologies. However, muscle architecture of VMO and VML has …

Skeletal muscle models are used to investigate motion and force generation in both
biological and bioengineering research. Yet, they often lack a realistic representation of the …

The multi-scale character of skeletal muscle models requires simulations with high spatial
resolution to capture all relevant effects. This naturally involves high computational load that …

Diffusion tensor imaging (DTI) has been widely used to characterise the 3D fascicle
architecture in muscle mechanics. However, the computational expense associated with …

Muscle fibre architecture is an important aspect of anatomy to consider when estimating
muscle properties. How fibre architecture varies across species specialising in different …

The tearing of a muscle-tendon complex (MTC) is caused by an eccentric contraction;
however, the structures involved and the mechanisms of rupture are not clearly identified …

Background and objective: Physiological cross-sectional area (PCSA) of a muscle plays a
significant role in determining the force contribution of muscle fascicles to skeletal …