[HTML][HTML] The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

V Sencio, MG Machado, F Trottein - Mucosal Immunology, 2021 - Elsevier
Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut
microbiota has a critical role in pulmonary immunity and host's defense against viral …

Respiratory viral infection-induced microbiome alterations and secondary bacterial pneumonia

S Hanada, M Pirzadeh, KY Carver… - Frontiers in …, 2018 - frontiersin.org
Influenza and other respiratory viral infections are the most common type of acute respiratory
infection. Viral infections predispose patients to secondary bacterial infections, which often …

Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia

L Bernard-Raichon, M Venzon, J Klein… - Nature …, 2022 - nature.com
Although microbial populations in the gut microbiome are associated with COVID-19
severity, a causal impact on patient health has not been established. Here we provide …

[HTML][HTML] Alterations in gut microbiota of patients with COVID-19 during time of hospitalization

T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan… - Gastroenterology, 2020 - Elsevier
Background & Aims Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infects gastrointestinal tissues, little is known about the roles of gut commensal microbes …

Alterations of the gut microbiota in patients with coronavirus disease 2019 or H1N1 influenza

S Gu, Y Chen, Z Wu, Y Chen, H Gao… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging serious global
health problem. Gastrointestinal symptoms are common in COVID-19 patients, and severe …

Pathogenesis of respiratory viral and fungal coinfections

F Salazar, E Bignell, GD Brown, PC Cook… - Clinical Microbiology …, 2022 - Am Soc Microbiol
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

[HTML][HTML] Gut dysbiosis during influenza contributes to pulmonary pneumococcal superinfection through altered short-chain fatty acid production

V Sencio, A Barthelemy, LP Tavares, MG Machado… - Cell reports, 2020 - cell.com
Secondary bacterial infections often complicate viral respiratory infections. We hypothesize
that perturbation of the gut microbiota during influenza A virus (IAV) infection might favor …

[HTML][HTML] Vaccination in the elderly: the challenge of immune changes with aging

A Ciabattini, C Nardini, F Santoro, P Garagnani… - Seminars in …, 2018 - Elsevier
The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …