Virus-like particles as antiviral vaccine: mechanism, design, and application

L Zhang, W Xu, X Ma, XJ Sun, JB Fan… - Biotechnology and …, 2023 - Springer
Virus-like particles (VLPs) are viral structural protein that are noninfectious as they do not
contain viral genetic materials. They are safe and effective immune stimulators and play …

Syntaxin 17 inhibits ischemic neuronal injury by resuming autophagy flux and ameliorating endoplasmic reticulum stress

L Chen, YF Xia, SF Shen, J Tang, JL Chen… - Free Radical Biology …, 2020 - Elsevier
Previous studies have shown that syntaxin 17 (STX17) is involved in mediating the fusion of
autophagosomes and lysosomes. This study aimed to investigate the role and mechanism of …

Narciclasine, a novel topoisomerase I inhibitor, exhibited potent anti-cancer activity against cancer cells

M Wang, L Liang, R Wang, S Jia, C Xu, Y Wang… - Natural Products and …, 2023 - Springer
DNA topoisomerases are essential nuclear enzymes in correcting topological DNA errors
and maintaining DNA integrity. Topoisomerase inhibitors are a significant class of cancer …

Protective effect of ligustrazine on oxidative stress and apoptosis following testicular torsion in rats

S Chen, Z Liao, T Zheng, Y Zhu, L Ye - Scientific Reports, 2023 - nature.com
Testicular torsion is a common urologic emergency and one of the causes of infertility in
males. It has been reported that ligustrazine may decrease oxidative stress and reduce …

Long term conjugated linoleic acid supplementation modestly improved growth performance but induced testicular tissue apoptosis and reduced sperm quality in male …

AM Abdelatty, OAM Badr, SA Mohamed, MS Khattab… - PLoS …, 2020 - journals.plos.org
Conjugated linoleic acid (CLA) is known for its multiple benefits including improvement of
growth, increasing lean mass, and anti-carcinogenic effects. However, when used in long …

Magnetic bead-based electrochemical and colorimetric methods for the detection of poly (ADP-ribose) polymerase-1 with boronic acid derivatives as the signal probes

N Xia, D Wu, T Sun, Y Wang, X Ren, F Zhao… - Sensors and Actuators B …, 2021 - Elsevier
Abstract Poly (ADP-ribose) polymerase-1 (PARP-1), as a highly conserved nuclear enzyme,
can catalyze the transfer of multiple ADP-ribose units from β-nicotinamide adenine …

Propofol synergizes with circAPBB2 to protect against hypoxia/reoxygenation‐induced oxidative stress, inflammation, and apoptosis of human cardiomyocytes

C Jin, S Yuan, L Piao, M Ren… - Immunity, Inflammation and …, 2023 - Wiley Online Library
Background Myocardial injury is the main manifestation of cardiovascular diseases, and
previous studies have shown that propofol (PPF) regulates myocardial injury. However, the …

[HTML][HTML] Protective effects of melatonin on testis histology following acute torsion-detorsion in rats

M Mirhoseini, FT Amiri, AAK Malekshah… - International Journal …, 2017 - ncbi.nlm.nih.gov
Background: Testicular damage due to spermatic cord torsion may lead to infertility. It is
probably because of changes in oxidative stress factors such as malondialdehyde …

iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer

Y Xue, H Han, L Wu, B Pan, B Dong, CC Yin… - Cell Death & …, 2017 - nature.com
Autophagy serves a critical function in the pathogenesis, response to therapy and clinical
outcome in cancers. Although a recent report showed a role of iASPP in suppressing …

Streptavidin-Conjugated DNA for the Boronate Affinity-Based Detection of Poly (ADP-Ribose) Polymerase-1 with Improved Sensitivity

F Gao, G Liu, Y Qiao, X Dong, L Liu - Biosensors, 2023 - mdpi.com
This work reports the development of a fluorescence method for the detection of poly (ADP-
ribose) polymerase-1 (PARP1), in which a phenylboronic acid-modified fluorescein …