Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …

COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

A Mittal, K Manjunath, RK Ranjan, S Kaushik… - PLoS …, 2020 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a newly emerging,
highly transmissible, and pathogenic coronavirus in humans that has caused global public …

Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike
(S) protein receptor-binding domain and block virus interactions with the cellular receptor …

N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2

M McCallum, A De Marco, FA Lempp, MA Tortorici… - Cell, 2021 - cell.com
Summary The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-
binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient …

A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2

R Amraei, W Yin, MA Napoleon, EL Suder… - ACS Central …, 2021 - ACS Publications
As the COVID-19 pandemic continues to spread, investigating the processes underlying the
interactions between SARS-CoV-2 and its hosts is of high importance. Here, we report the …

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

M Thépaut, J Luczkowiak, C Vivès, N Labiod… - PLoS …, 2021 - journals.plos.org
The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history.
Despite early identification of ACE2 as the receptor for viral spike protein, much remains to …

Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules

M Stravalaci, I Pagani, EM Paraboschi, M Pedotti… - Nature …, 2022 - nature.com
The humoral arm of innate immunity includes diverse molecules with antibody-like functions,
some of which serve as disease severity biomarkers in coronavirus disease 2019 (COVID …

Can SARS-CoV-2 virus use multiple receptors to enter host cells?

LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review

A Elhabyan, S Elyaacoub, E Sanad, A Abukhadra… - Virus research, 2020 - Elsevier
Background Susceptibility to severe viral infections was reported to be associated with
genetic variants in immune response genes using case reports and GWAS studies. SARS …