Recent studies highlight the great potential impact of HDAC inhibitors (HDACis) in
suppressing TNBC, even though clinical trials including a single HDACis demonstrated …

The nitric oxide (NO)–cyclic guanosine monophosphate (cGMP)–protein kinase G (PKG)
pathway plays a critical role in skeletal homeostasis. Preclinical data using NO and its …

Abstract Countries of the Persian Gulf region—Bahrain, Iran, Iraq, Kuwait, Oman, Qatar,
Saudi Arabia, and United Arab Emirates—have become increasingly modernized, resulting …

Osteoporosis, a condition associated with significant morbidity and mortality, is prevalent in
the growing elderly population. Aging is associated with characteristic changes in the …

Rapid mineralization of cultured osteoblasts could be a useful characteristic in stem cell-
mediated therapies for fracture and other orthopedic problems. Dimethyl sulfoxide (DMSO) …

Research in the last decade has revealed that bone is not only a target tissue for numerous
circulating hormones but functions as an endocrine organ itself. As a recent study …

Objective: Chronic critical illness (CCI), characterized by prolonged mechanical ventilation
and tracheostomy, commonly manifests with elevated bone resorption, which has previously …

Tooth movement, as it is generally visualized by orthodontist clinicians, is modeled as a
biological event mediated by the cells of the periodontal ligament (PDL) whereby alveolar …

Objective To discuss the emerging roles of bariatric surgery and clinical endocrinology
within the context of obesity and diabetes mellitus comprehensive care plans and cost …

To maintain calcium and phosphate balance despite declining kidney function, adaptations
must begin in the earliest stages of chronic kidney disease (CKD). These are generally …