Biomarker research in Parkinson's disease using metabolite profiling

JF Havelund, NHH Heegaard, NJK Færgeman… - Metabolites, 2017 - mdpi.com
Biomarker research in Parkinson's disease (PD) has long been dominated by measuring
dopamine metabolites or alpha-synuclein in cerebrospinal fluid. However, these markers do …

Pediatric adrenocortical carcinoma

M Ilanchezhian, DG Varghese, JW Glod… - Frontiers in …, 2022 - frontiersin.org
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy of the adrenal gland with
an unfavorable prognosis. It is rare in the pediatric population, with an incidence of 0.2-0.3 …

Advances in sample extraction

S Tang, H Zhang, HK Lee - Analytical chemistry, 2016 - ACS Publications
Analyte or sample extraction is the most basic, yet a very important and dominant, feature of
any sample preparation technique which in general can also include other processes such …

Differential effects of MDMA and methylphenidate on social cognition

Y Schmid, CM Hysek, LD Simmler… - Journal of …, 2014 - journals.sagepub.com
Social cognition is important in everyday-life social interactions. The social cognitive effects
of 3, 4-methylenedioxymethamphetamine (MDMA,'ecstasy') and methylphenidate (both used …

Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination

CM Hysek, LD Simmler, N Schillinger… - International journal …, 2014 - academic.oup.com
Abstract Methylphenidate and 3, 4-methylenedioxymethamphetamine (MDMA,'ecstasy') are
widely misused psychoactive drugs. Methylphenidate increases brain dopamine and …

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

F Petrelli, G Dallérac, L Pucci, C Calì, T Zehnder… - Molecular …, 2020 - nature.com
Astrocytes orchestrate neural development by powerfully coordinating synapse formation
and function and, as such, may be critically involved in the pathogenesis of …

In matrix derivatization combined with LC-MS/MS results in ultrasensitive quantification of plasma free metanephrines and catecholamines

M van Faassen, R Bischoff, K Eijkelenkamp… - Analytical …, 2020 - ACS Publications
Plasma-free metanephrines and catecholamines are essential markers in the biochemical
diagnosis and follow-up of neuroendocrine tumors and inborn errors of metabolism …

Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover …

L Bally, T Zueger, T Buehler, AS Dokumaci, C Speck… - Diabetologia, 2016 - Springer
Aims/hypothesis To investigate exercise-related fuel metabolism in intermittent high-intensity
(IHE) and continuous moderate intensity (CONT) exercise in individuals with type 1 diabetes …

Simultaneous analysis of multiple neurotransmitters by hydrophilic interaction liquid chromatography coupled to tandem mass spectrometry

S Tufi, M Lamoree, J de Boer, P Leonards - Journal of Chromatography A, 2015 - Elsevier
Neurotransmitters are endogenous metabolites that allow the signal transmission across
neuronal synapses. Their biological role is crucial for many physiological functions and their …

Sympathetic activity and early mobilization in patients in intensive and intermediate care with severe brain injuries: a preliminary prospective randomized study

A Rocca, JM Pignat, L Berney, J Jöhr, D Van de Ville… - BMC neurology, 2016 - Springer
Background Patients who experience severe brain injuries are at risk of secondary brain
damage, because of delayed vasospasm and edema. Traditionally, many of these patients …