Vaccines as alternatives to antibiotics for food producing animals. Part 2: new approaches and potential solutions

K Hoelzer, L Bielke, DP Blake, E Cox, SM Cutting… - Veterinary …, 2018 - Springer
Vaccines and other alternative products are central to the future success of animal
agriculture because they can help minimize the need for antibiotics by preventing and …

Spore formation in Bacillus subtilis

IS Tan, KS Ramamurthi - Environmental microbiology reports, 2014 - Wiley Online Library
Although prokaryotes ordinarily undergo binary fission to produce two identical daughter
cells, some are able to undergo alternative developmental pathways that produce daughter …

Structure, assembly, and function of the spore surface layers

AO Henriques, CP Moran, Jr - Annu. Rev. Microbiol., 2007 - annualreviews.org
Endospores formed by Bacillus, Clostridia, and related genera are encased in a protein
shell called the coat. In many species, including B. subtilis, the coat is the outermost spore …

Select what you need: a comparative evaluation of the advantages and limitations of frequently used expression systems for foreign genes

J Yin, G Li, X Ren, G Herrler - Journal of biotechnology, 2007 - Elsevier
The expression of heterologous proteins in microorganisms using genetic recombination is
still the high point in the development and exploitation of modern biotechnology. People can …

Immunity in response to particulate antigen-delivery systems

T Storni, TM Kündig, G Senti, P Johansen - Advanced drug delivery reviews, 2005 - Elsevier
Adjuvants and antigen-delivery systems are essential in inducing and modifying immune
responses, and despite the variety of materials available for such use, mechanisms by which …

Applications of Bacillus subtilis spores in biotechnology and advanced materials

X Zhang, A Al-Dossary, M Hussain… - Applied and …, 2020 - Am Soc Microbiol
The bacterium Bacillus subtilis has long been an important subject for basic studies.
However, this organism has also had industrial applications due to its easy genetic …

Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: Set the bugs to work?

F Farjadian, M Moghoofei, S Mirkiani, A Ghasemi… - Biotechnology …, 2018 - Elsevier
Drug delivery is a rapidly growing area of research motivated by the nanotechnology
revolution, the ideal of personalized medicine, and the desire to reduce the side effects of …

An overview and future prospects of recombinant protein production in Bacillus subtilis

H Yang, J Qu, W Zou, W Shen, X Chen - Applied Microbiology and …, 2021 - Springer
Bacillus subtilis is a well-characterized Gram-positive bacterium and a valuable host for
recombinant protein production because of its efficient secretion ability, high yield, and non …

Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B

P Permpoonpattana, HA Hong… - Infection and …, 2011 - Am Soc Microbiol
Clostridium difficile is a leading cause of nosocomial infection in the developed world. Two
toxins, A and B, produced by most strains of C. difficile are implicated as virulence factors …

Oral vaccination of tilapia against Streptococcus agalactiae using Bacillus subtilis spores expressing Sip

YY Yao, DD Chen, ZW Cui, XY Zhang, YY Zhou… - Fish & shellfish …, 2019 - Elsevier
Streptococcus agalactiae infections are becoming an increasing problem in aquaculture
because of significant morbidity and mortality, which restricts the healthy development of …