Diversity in chemical structures and biological properties of plant alkaloids

S Bhambhani, KR Kondhare, AP Giri - Molecules, 2021 - mdpi.com
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …

Phytosterols and their derivatives: Structural diversity, distribution, metabolism, analysis, and health-promoting uses

RA Moreau, L Nyström, BD Whitaker… - Progress in Lipid …, 2018 - Elsevier
Phytosterols (plant sterols) occur in the cells of all plants. They are important structural
components that stabilize the biological membranes of plants. Sterols can occur in the “free” …

Generation of α-solanine-free hairy roots of potato by CRISPR/Cas9 mediated genome editing of the St16DOX gene

M Nakayasu, R Akiyama, HJ Lee, K Osakabe… - Plant Physiology and …, 2018 - Elsevier
Potato (Solanum tuberosum) is a major food crop, while the most tissues of potato
accumulates steroidal glycoalkaloids (SGAs) α-solanine and α-chaconine. Since SGAs …

Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato

S Sawai, K Ohyama, S Yasumoto, H Seki… - The Plant …, 2014 - academic.oup.com
Potatoes (Solanum tuberosum) contain α-solanine and α-chaconine, two well-known toxic
steroidal glycoalkaloids (SGAs). Sprouts and green tubers accumulate especially high levels …

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway

PD Cárdenas, PD Sonawane, J Pollier… - Nature …, 2016 - nature.com
Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by
solanaceous species. They contribute to pathogen defence but are toxic to humans and …

Solanum steroidal glycoalkaloids: structural diversity, biological activities, and biosynthesis

DK Zhao, Y Zhao, SY Chen, EJ Kennelly - Natural product reports, 2021 - pubs.rsc.org
Covering: up to 1 October 2020 Solanum steroidal glycoalkaloids (SGA), characterized by
nitrogenous steroidal aglycone and glycoside residues, mainly occur in the Solanum …

GLYCOALKALOID METABOLISM1 is required for steroidal alkaloid glycosylation and prevention of phytotoxicity in tomato

M Itkin, I Rogachev, N Alkan, T Rosenberg… - The Plant …, 2011 - academic.oup.com
Steroidal alkaloids (SAs) are triterpene-derived specialized metabolites found in members of
the Solanaceae family that provide plants with a chemical barrier against a broad range of …

Genome Editing for Crop Improvement – Applications in Clonally Propagated Polyploids With a Focus on Potato (Solanum tuberosum L.)

SS Nadakuduti, CR Buell, DF Voytas… - Frontiers in plant …, 2018 - frontiersin.org
Genome-editing has revolutionized biology. When coupled with a recently streamlined
regulatory process by the US Department of Agriculture and the potential to generate …

The bitter side of the nightshades: Genomics drives discovery in Solanaceae steroidal alkaloid metabolism

PD Cárdenas, PD Sonawane, U Heinig, SE Bocobza… - Phytochemistry, 2015 - Elsevier
Steroidal alkaloids (SAs) and their glycosylated forms (SGAs) are toxic compounds largely
produced by members of the Solanaceae and Liliaceae plant families. This class of …

Antioxidants in potatoes: A functional view on one of the major food crops worldwide

H Hellmann, A Goyer, DA Navarre - Molecules, 2021 - mdpi.com
With a growing world population, accelerating climate changes, and limited arable land, it is
critical to focus on plant-based resources for sustainable food production. In addition, plants …