Establishment of nanoparticle screening technique: A pivotal role of sodium carboxymethylcellulose in enhancing oral bioavailability of poorly water-soluble …

S Cheon, JS Kim, MR Woo, SH Ji, S Park… - International Journal of …, 2024 - Elsevier
A novel nanoparticle screening technique was established to mostly enhance the aqueous
solubility and oral bioavailability of aceclofenac using nanoparticle systems. Among the …

Glibenclamide–malonic acid cocrystal with an enhanced solubility and bioavailability

D Srivastava, Z Fatima, CD Kaur, A Mishra… - Drug Development …, 2022 - Taylor & Francis
Objective The objective of the work is to enhance the solubility, dissolution, and
pharmacokinetic properties of glibenclamide (GLB) via cocrystallization technique …

Physicomechanical, stability, and pharmacokinetic evaluation of aceclofenac dimethyl urea cocrystals

H Afzal, N Abbas, A Hussain, S Latif, K Fatima… - AAPS …, 2021 - Springer
Poor physicomechanical properties and limited aqueous solubility restrict the bioavailability
of aceclofenac when given orally. To improve its above properties, aceclofenac (ACE) was …

RS, S (+)-and R (-)-ibuprofen cocrystal polymorphs: vibrational spectra, XRD measurement and DFT calculation studies

Y Jing, Q Zhao, J Zhang, J Xue, J Liu, J Qin, Z Hong… - Heliyon, 2025 - cell.com
In this paper, cocrystal polymorphs of RS-ibuprofen (RS-IBU), S (+)-ibuprofen (S (+)-IBU), R (-
)-ibuprofen (R (-)-IBU) with nicotinamide (NIC) were synthesized by different methods. RS …

Synthesis, characterization, and dissolution properties of Aceclofenac-isobutabolammonium salt

PV Bagwe, VP Thakur, PS Kharkar, SV Joshi - Journal of the Indian …, 2023 - Elsevier
The solubility issues of Biological Classification System Class II drugs are a challenge for
formulation, and salt formation is a potential solution. In this study, we report the synthesis …

[PDF][PDF] Studies on Formulation and Evaluation of Clotrimazole Cocrystals

H Desai, A Rajadhyax, S Jaiswal… - World Journal of …, 2022 - researchgate.net
Cocrystallization uses the approach of hydrogen bonding between a drug and a GRAS
coformer to form a multicomponent crystalline compound with different physicochemical …

Експериментальне дослідження фармакодинаміки та фармакокінетики кристалічних форм похідних 4-R-2, 2-діоксо-1Н-2λ6, 1-бензотіазин-3-карбонових …

ПС Бондаренко - 2021 - dspace.vnmu.edu.ua
Дослідження присвячене вирішенню актуального завдання фармакології-пошуку
перспективних речовин з аналгетичною та протизапальною активністю серед похідних …