There has been an increasing prevalence of neurodegenerative diseases with the rapid
increase in aging societies worldwide. Biomarkers that can be used to detect pathological …

There is a pressing need for disease-modifying therapies in patients suffering from
neurodegenerative diseases, including Parkinson's disease (PD). However, these disorders …

Background Cognitive deficits are among the main disabling symptoms in COVID-19
patients and post-COVID syndrome (PCS). Within brain regions, the hippocampus, a key …

Background: Amyloid-ß (Aß) and tau protein accumulation in the brain is thought to be one
of the causes of Alzheimer's disease (AD). Recent study found that the glymphatic system …

Multi-compartment modelling of white matter microstructure using Neurite Orientation
Dispersion and Density Imaging (NODDI) can provide information on white matter health …

Aging is associated with deterioration in dentate gyrus (DG) and CA3, both crucial
hippocampal subfields for age susceptible memory processes such as mnemonic …

Introduction Free‐water (FW) imaging, a new analysis method for diffusion magnetic
resonance imaging (MRI), can indicate neuroinflammation and degeneration. We evaluated …

Objective White matter damage is a feature of Alzheimer's disease, yet little is known about
how facets of the Alzheimer's disease process relate to key features of white matter structure …

The microstructural characteristics of white and gray matter in mild cognitive impairment
(MCI) and the early-stage of Alzheimer's disease (AD) remain unclear. This study aimed to …

Objective To characterise in vivo the microstructural abnormalities of multiple sclerosis (MS)
normal-appearing (NA) cortex and cortical lesions (CLs) and their relations with clinical …