Inflammasome activation at the crux of severe COVID-19
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19
JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …
[HTML][HTML] Longitudinal analyses reveal immunological misfiring in severe COVID-19
Recent studies have provided insights into the pathogenesis of coronavirus disease 2019
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …
(COVID-19),,–. However, the longitudinal immunological correlates of disease outcome …
[HTML][HTML] Detection of viral infections by innate immunity
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …
innate immune system as they detect conserved viral pathogen-associated molecular …
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …
[HTML][HTML] Multi-organ proteomic landscape of COVID-19 autopsies
X Nie, L Qian, R Sun, B Huang, X Dong, Q Xiao… - Cell, 2021 - cell.com
The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
A bibliometric analysis of pyroptosis from 2001 to 2021
D Ma, B Yang, B Guan, L Song, Q Liu, Y Fan… - Frontiers in …, 2021 - frontiersin.org
Background Pyroptosis is a new programmed cell death discovered in recent years.
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …
COVID-19-associated gastrointestinal and liver injury: clinical features and potential mechanisms
P Zhong, J Xu, D Yang, Y Shen, L Wang… - Signal transduction and …, 2020 - nature.com
Abstract Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The infection is spreading globally and poses a …
syndrome coronavirus 2 (SARS-CoV-2). The infection is spreading globally and poses a …
Coronavirus disease 2019–associated thrombosis and coagulopathy: review of the pathophysiological characteristics and implications for antithrombotic management
L Ortega‐Paz, D Capodanno… - Journal of the …, 2021 - Am Heart Assoc
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by severe
acute respiratory syndrome coronavirus‐2, which has posed a significant threat to global …
acute respiratory syndrome coronavirus‐2, which has posed a significant threat to global …
Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications
A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …