Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular
defense mechanisms as well as physiological functions, and intracellular signaling …

Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

The development of realistic in vitro blood–brain barrier (BBB) models that recapitulate the
physiological parameters and molecular aspect of the neurovascular unit (NVU) is of …

Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural
plasticity and improve cognitive impairment. The purpose of this study was to investigate the …

The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …

Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Ursolic acid (UA) is a pentacyclic triterpene which is found in common herbs and medicinal
plants that are reputed for a variety of pharmacological effects. Both as an active principle of …

This literature review focuses on the underlying pathophysiology of TBI and PTSD
symptoms, while also examining the plethora of stem cell treatment options to ameliorate …

Traumatic brain injury (TBI) is a major cause of injury-related mortality and morbidity in the
USA and around the world. The survivors may suffer from cognitive and memory deficits …