Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

“Then Helen, Zeus' daughter, bethought her of another matter. She drugged the wine with an
herb that banishes all care, sorrow, and ill humor. Whoever drinks wine thus drugged cannot …

Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is
on the rise, in parallel with global rates. Many risk factors associated with NCDs are …

Background A fixed-dose combination therapy (polypill strategy) has been proposed as an
approach to reduce the burden of cardiovascular disease, especially in low-income and …

In the past, communicable diseases caused the highest mortality in Iran. Improvements in
socioeconomic status and living standards including access to safe drinking water, along …

Background & Aims Northeast Iran has one of the highest reported rates of esophageal
squamous cell carcinoma (ESCC) worldwide. Decades of investigations in this region have …

Background Evidence is emerging for a role of opiates in various cancers. In this study, we
aimed to investigate the association between regular opium use and cancer incidence …

Background: There is considerable variation in hypertension prevalence and awareness,
and their correlates, across different geographic locations and ethnic groups. We performed …

Background For a better understanding of the current situation of drug use in Iran, we
utilized the network scale-up approach to estimate the prevalence of illicit drug use in the …

Smoking, heavy alcohol drinking and drug abuse are detrimental lifestyle factors leading to
loss of million years of healthy life annually. One of the major health complications caused …